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Pteridines, Official Journal of ISP, ISSN 0933-4807

The best papers published in PTERIDINES per year by 

first author scientists younger than 40 years will be arwaded 

with € 1000.-- and € 500.-- provided by the International Society of Pteridinology.

Please submit original manuscripts as word-documents via e-mail to:

Prof. Dr. Dietmar Fuchs
Division of Biological Chemistry Biocentre
Innsbruck Medical University
Fritz Pregl Strasse 3, A-6020 Innsbruck, Austria
Phone: +43 512 9003 70350, Fax: +43 512 9003 73330
e-mail:
dietmar.fuchs@i-med.ac.at


1989, volume 1

Wachter H, Werner ER, Reibnegger G, Fuchs D, Hausen A
Neopterin in Clinical Use 
3

Haavik J, Andersson KK, Petersson L, Flatmark T
Native and Phosphorylated Bovine Adrenal Tyrosine 3-Monooxygenase. Interactions with Tetrahydropterin and Substrate and Stability of the Formed 4a-Hydroxy-Tetrahydrobiopterin
11

Auzeby A, Bogdan A, Krosi Z, Touitou Y
Large-Amplitude Circadian Variatons of Urinary Neopterin in Healthy Man
17

Mura P, Barriere M, Papet Y, Reiss D, Camenen I, Vaillant L, Lorette G
The Clinical Significance of Urinary Neopterin in the Follow-up of Patients after Exercise of Malignant Melanoma
19

Goldberg M, Naumann J, Wittmann J, Merkenschlager M
Pteridine Pattern of the Developing Chick Embryo
23

Goldberg M,. Gassner F, Merkenschlager M
Studies and Comparison of Urinary Pteridine Patterns in Dogs and Cats and their Alteration in Various Neoplasias and Virus Infection
29

Benkovic SJ, Adams JA, Fierke CA, Naylor AM
Insights into Enzymic Catalysis from Studies on Dihydrofolate Reductases
37

Bartke M, Pfleiderer W
Pteridines, LXXXVIII. Ocidations and Reactions of 2- and 4- Thiolumazine Derivatives. Synthesis and Properties of Pteridine-Sulfinates and –Sulfonates
45

Bartke M, Pfleiderer W
Pteridines, IXC. Synthesis, Oxidations and Reactions of 6- and 7-Hydroxy-2-Thiolumazines
57

Vitols KS, Montejano YD, Kuefner U, Huennekens FM
Selective Cytotocicity of Carboxypeptidase-activated Methotrexate α-Peptides
65

Matsuura S, Traub H, Armarego WLF
Synthesis and Dihydropteridine Reductase [EC 1.6.99.10] (Human) Activity of Reduced 2-7-dimethylpteridin-4(3H)-one, 2-methyl-2desamino-neopterin [6-(1´S,2´R-1´,2´,3´-trihydroxypropyl)-2-methylpteridin-4(3H)-one] and 2-methyl-2-desaminobiopterin
[6-(1´R,2´S-1´,2´-dihydroxypropyl)-2-methylpteridin-4(3H)-one]
73 

Bartke M, Pfleiderer W
Pteridines, XC. Syntheses, Oxidations, Properties, and Reactions of 2-Thiopteridine-4,6-7trione Derivatives
83 

Rosowsky A, Bader H, Forsch RA
Synthesis of the Folylpolyglutamate Synthetase Inhibitor Nα-Pteroyl-L-ornithine and its Nδ-Benzoyl and Nδ-Himiphthaloyl Derivatives, and an Improved Synthesis of Nά-(4-Amino-4-deoxypteroyl)-Nδ-himiphthaloyl-L-ornithine
91 

Kohashi M, Takahashi A, Iwai K
Separation and Determination of Tetrahydrofolyopolyglutamates and their 5-Methyl Derivatives by Reversed-Phase High-Perfomance Liquid Chromatography with Electrochemical Detecton
99 

Sueoka T, Katoh S
Enzymatic Isomerization of Sepiapterin to 6-1´-Hydroxy-2´-oxopropyl 7,8 dihydropterin
103 

Altmann P, Hamon C, Sawyer N, Cunningham J, Marsh F, Blair J
Pterin Metabolism in Haemodialysis Patients
111 

Reibnegger G, Fuchs D, Hausen A, Schmutzhard E, Werner ER, Werner-Felmayer G, Dierich MP, Wachter H
Correlation of Serum Interferon Gamma and Neopterin Concentrations in Africans with Various Diseases
119 

Norman M, Bremme K, Eneroth P
Immune Markers in pregnancy. A Study on Neopterin, β2-Microglobulin, Deoxythymidine Kinase and C-Reactive protein
125 

Valsasina R, Riva E, Biasucci G, Longhi R, Giovanni M
Italian Study on the Pteridines Metabolism in Children Affected by Hyperphenylalaninaemia and Phenylketonuria
129

Abou-Hadeed K, Schulz BS, Pfleiderer W
Pteridines, XCIII, Reactions of 6-Chloro-, 7-Chloro- and 6,7-Dichloro-1,3-dimethyllumazines with N-Nucleophiles
133

Rosowsky A, Cheng-Sein Y
A Convenient Method of Esterificantion of Leucovorin Under Non-Acidic Conditions 
143

Heales SJR, Hyland K
Production of Stable Solutions of 7,8-Dihydropterin
151

Coppell AD, Leeming RJ, Blair JA
Identififcation of Folates by Iodine Oxidation at Acid, Neutral and Alkaline pH
155

Brody T
The Influence of Folate Binding Proteins on 1-Carbon Metabolism. A Review
159

Denz HA, Grünewald K, Thaler J, Huber H, Fuchs D, Hausen A
Reibnegger G, Werner ER, Wachter H
Urinary Neopterin as a Prognostic Factor in Haematological Neoplasias
167

Manteuffel-Cymborowska M, Chmurzynska W, Kaminska B, Sikora E, Grzelakowska-Sztabert B
In Vitro and in Vivo Effects of Alkyl Nitrites on Methionine Synthase from Mouse Kidney and Liver 
171

Sikora E, Krzyanowski L, Rzezotarska B
Rapid A, Sensitive, Nonradioactive Assay for Serum a-Glutamyl Hydrolase Using Synthetic N-(4-Aminobenzoyl)-g-oligo (L-glutamic Acids) as Substrates 
175

Armarego WLF
Structure-Activity Studies of Pteridine Cofactors with Dihydropteridine Reductase
179

Steinerstauch P, Sawada Y, Leimbacher W, Ghisla S, Curtius HCh
Purification and Characterization of a Carbonyl Reductase from Human Liver,
which is Competent in the Reduction of 6-Pyruvoyl-Tetrahydropterin 
189

Lockart RJ, Pfleiderer W
Pteridines, XCV. Synthesis of New N-5-Acyl-5,6,7,8-tetrahydropterins
199

Abstracts: 9th Winter Workshop on Biochemical and Clinical Aspects of Pteridines
February 10th -17th, 1990, St.Christoph, Arlberg, Austria
211

Hansen SI, Holm J, Hoier-Madsen M
Quantitiation of the Folate Binding Protein in Human Cerebrospinal Fluid by an Enzyme-linked Immunosorbent Assay (ELISA) 
231

Carty MP, Beirne E, Donlon J
High Protein Diet and Phenylalanine Hydroxylase Activities in Rats
235

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1990, volume 2

Alkorta I, Goya P, Paez JA, Pfleiderer W
Synthesis and Physico-Chemical Properties of 6- and 7-Monosubstituted Pyrazino/2,3-c/-1,2,6-Thiadiazine 2,2-Dioxides 
3

Al-Masoudi NAL, Pfleiderer W
Nucleosides, XLVII. Syntheses, Reactions and Properties of 6- and 7-p-Bromophenyllumazine N-1-Nucleosides 
9

Reibnegger G, Denz HA, Fuchs D, Fuith LC, Gattringer C, Hausen A, Huber H, Werner ER, Werner-Felmayer G, Wachter H
Neopterin and Cellular Immune Activation in Active Gynecological Cancer: Significant Correlation Between Neopterin and Circulating Number of HLA-DR Expressing Lymphocytes
17

Granditsch G, Fuchs D, Hausen H; Reibnegger G, Werner ER, Werner-Felmayer G, Wachter H
Urinary Neopterin as Marker for Disease Activity in Children and Adolescents with Crohn’s Disease
23

Abstracts: 4th International Conference on Pteridines and Related Biogenic Amines
March 3th -8th,1990, Champfer, St. Moritz, Switzerland

29

Hanneken L, Cremer-Bartels G, Gerdinga H, Krause K
GTP-CH Activity in Bovine Retina 
45

Ambach E, Tributsch W, Fuchs D, Hausen A, Reibnegger G, Wachter H
Post Mortem Neopterin Concentrations in Sudden Infant Death Syndome (SIDS)
47

Caruso A, de Francesco M, Gonzales R, Pollara P, Zanoni L, Foresti I, Turano A
Four Different Markers for Activated Cell Mediated Immunity Compared with the Clinical Stages of HIV Infection 
51

Andreesen R, Scheibenbogen C, Kreutz M, Krause S, Rehm A
Regulation of Neopterin Secretion during Human Monocyte to Macrophage Differentiation in Vitro
59

Soyka R, Pfleiderer W
Pteridines, XCVI, Synthesis and Reactions of 6-(1,2,3-Trihydroxypropyl)-pteridines
63

Li M, Collier C, Gritsmann H, Bertino JR
Activity of 5, 10 -Methenyltetrahydrofolate Synthetase in Rat Tissues and in Tumor Cells Lines 
75

Hutterer J, Fuchs D, Reibnegger G, Wallner G, Vetter N, Wachter H
Neopterin Changes during Zidovudine Treatment of HIV-1 Infection
81

Hausen A, Fuchs D, Reibnegger G, Werner ER. Werner-Felmayer G, Wachter H
Reduction of Ferric Iron by 7,8-Dihydroneopterin
83

Zangerle R, Fritsch P, Fuchs D, Wachter H
Is Neopterin Helpful in Distinguishing between Different Disease Patterns in AIDS
87

Moeller AA, Fuchs D, Reibnegger G, Zaudig M, Werner ER, Wachter H
Changes of Neopterin and Tryptophan in Serum and Cerebrospinal Fluid of Patients in Different Stages of HIV-1 Infection
91

Robin B, Fuchs D, Koller W, Wachter H
Course of Immune Activation Markers in Patients after Severe Multiple Trauma
95

Leohirun L, Pholcharoen T, Sumethkul V, Thuvasethakul P, Panichpant S, Boonpucknavig S, Boonpucknavig V
Urinary Neopterin in Glomerulonephritis
99

Crème-Bartels G, Gerding H, Hanneken L, Krause K
Isoxanthopterin Excretion of Rats with Inherited Retinal Dystrophy
103

Denz H, Fuchs D, Hausen H, Huber H, Nachbaur D, Reibnegger G, Thaler J, Werner ER, Wachter H
Urinary Neopterin in Monoclonal Gammopathies
107

Abstracts: 10th Winter Workshop on Biochemical and Clinical Aspects of Pteridines
February 16th -23th, 1991, St.Christoph/Arlberg, Austria

111

Ferre J, Jacobson KB, Pfleiderer W
Proposal towards a Normalization of Pteridines Nomenclature
129

Rosowsky A, Forsch RA, Moran RG, Freisheim JH
Synthesis and in Vitro Biological Evaluation of g,b-Methano Analogues of Methotrexate and Aminopterin
133

Sugimoto T, Ogiwara S, Kiuchi K, Nagatsu T, Sakai M, Nagatsu I, Fujita K
An Enzyme Immunoassay for Neopterin and Biopterin Using a Microtitre Plate Linked with N-(3-Aminopropyl) Derivatives of Pteridines
141

Fuchs D, Hausen H, Reibnegger G, Werner ER, Werner-Felmeyer G, Wachter H
Distinct Neopterin Excretion Patterns after Vaccination
147

Takikawa SI, Matsuura S
Enzymatic Synthesis of Four Stereoisomers of 7-Oxo-biopterin and Determination of the Absolute Structure of Ichthyopterin
151

Zuccotti GV, Biasucci G, Brioschi V, Locatelli V, Antonucci A, Riva E, Giovannini M.
Urinary Neopterin Antigenaemia and CD4/CD8 Ratio in HIV Positive Children under AZT Therapy
157

Mayr P, Fuchs D, Fuith LC, Reibnegger G, Werner ER, Wachter H
Pregnancy Increases Urinary Neopterin Levels in Human Immunodefiency Virus Type 1 Infection 
161

Samsonov M, Nassonov E, Masenko V, Naumov V, Mareev V, Belenkov Y
Serum Neopterin - Possible Marker to Predict Progression of Dilated Cardiomyopathy
165

Katzenmeier G, Schwarzkopf B, le Van Q, Schmid C, Bacher A
Preparation of Isotope-labeled Dihydroneopterin 3’-Triphsophate with High Specific Activity
169

Tsusue M, Kuroda S, Sawada H
Localization of Sepiapterin Deaminase and Pteridines in the Granules in Epidermal Cells of the Silkworm, Bombyx mori
175

Nair CPP; Stockstad ELR
Effect of Hormones and Protein Level on Induction of Enzymes Involved in Histidine Degradation and Folate Metabolism
183

Schuster V, Reibnegger G, Wachter H
Neopterin and Endogenous Interferon Gamma in Serum of Patients with Epstein-Barr Virus-associated Limphoproliferative Diseases
189

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1991/92, volume 3

Contributions: Pterins, Folates and Biogenic Amines in Neurology, Pediatrics and Immunology; February 16th - 22nd 1991, Palm Cove near Cairns, Queensland, Australia (Cotton RGH, Blau N, Curtius H Ch, Levine RA, eds.)
1

Güttler F
Molecular Basis for the Phenotypic Diversity of Phenylketonuria
5

Dianzani I, Camaschella C, Ferrero GB, De Sanctis L, Ponzone A, Cotton RGH
Molecular Basis of Phenylketonuria in Italy 
11

Spada M, Parrella T, Ponzone R, Ferraris S, Guardamagna O, Ponzone A, Blau N
Monitoring Treatment in Tetrahydrobiopterin Deficiency
13

Shintaku H, Nakajima T, Sawada Y, Hase Y, Fujioka M, Nishimura A, Isshiki G, Oura T, Hsiao KJ, Chen RG
Prenatal Diagnosis of Tetrahydrobiopterin (BH4) Synthase Deficiency
17

Guardamagna O, Spada M, Ponzone A, Viora E, Ponzone R, Binkert F, Matasovic A, Kierat L, Blau N
Prenatal Diagnosis of Dihydropteridine Reductase Deficiency in a Twin Pregnancy
19

Cerone R, Fantasia AR, Schiaffino MC, Maritano L, Romano T
Non-responsive Dihydropteridine Reductase Deficiency
23

Adler C, Curtius HC, Wetzel E, Giudici TA, Blaskovics M, Viscontini M
7-Substituted Pterins: Loading Experiments with 3’-Mono Deuterated Tetrahydro-L-Biopterin
25

Curtius HC, Rebrin I, Kuster T, Adler C
7-Substituted Pterins: Formation in Carbinolamine Dehydratase Deficiency
29

Blaskovics ME, Giudici TA, Blau N, 
Primapterinuria: A Clinical Update
33

Nakajima T, Shintaku H, Sawada Y, Fujioka M, Nishimura A, Isshiki G, Ohura T
Fetal Guinea-Pig Model for Tetrahydrobiopterin Deficiency
35

Dhondt JL, Millot F, Hayte JM, Forzy G, Mazingue F, Pfleiderer W, Farriaux JP
Intravenous Infusion of High Dose Methotrexate, Metabolism of Pteridines and Consequences for the Tetrahydrobiopterin Dependent Hydroxylases
37

Ichinose H, Katoh S, Sueoka T, Titani K, Fujita K, Nagatsu T
Cloning and Sequencing of cDNA Encoding Human Sepiapterin Reductase
41

Guzman J, Blau N
6-Pyruvoyl Tetrahydropterin Synthase in Human Tissues and Cell Lines
43

Katoh S, Sueoka T, Kurihara T
Stereostructure and Reactivity of 6-Pyruvoyl Tetrahydropterin Molecule Estimated by Molecular-Orbital Method
47

Werner ER, Mayer B, Prast H, Schmidt K, Werner-Felmayer G, Weiss G, Wachter H
Current Knowledge on Pteridine Dependence of Nitric Oxide Synthase
49

Nunokawa Y, Aisaka K, Kanai T, Noguchi T, Ishihara T
(6R)-5,6,7,8-Tetrahydro-L-Biopterin-Dependent Activation of Soluble Guanylate Cyclase in the Rat Cerebellum is Mediated by Nitric Oxide Formation 
51

Werner-Felmayer G, Werner ER, Weiss G, Wachter H.
Tetrahydrobiopterin-Dependent Conversion of L-Arginine to L-Citrulline and Nitric Oxide in Murine and Human Cells
53

Rebrin I, Petruschka L, Curtius HCh, Adler C, Herrmann FH
Human Liver Pterin 4a-Carbinolamine Dehydratase.
Purification and Characterization
55

Petruschka L, Rebrin I, Grimm U, Herrmann FH
Biochemical and Immunological Characterization of Rat and Human Phenylalanine Hydroxylase 
59

Kuhn DM, Johansen P, Jennings I, Cotton RGH
Tryptophan Hydroylase and Protein Kinase Interactions; Does Phosphorylation Cause Activation?
61

Watanabe Y, Mataga N, Hayashi T, Ishihara T, Kanai T, Noguchi T, Miwa S, Watanabe Y
Molecular Mechanisms of Tetrahydrobiopterin Action on Neurotransmitter Release
63

Tani Y, Ohno T, Ishihara T, Kanai T, Noguchi T
Age-Related Changes in Brain 6R-L-erythro-5,6,7,8-Tetrahydrobiopterin (R-THBP) and Biogenic Amine Levels in Fischer-344 Rats
65

Nakanishi N, Onozawa S, Matsumoto R, Nakamura M, Imagawa S, Yamada S
Effect of Nerve Growth Factor and Dibutyryl Cyclic AMP on Biopterin and Catecholamine Levels of PC 12h Pheochromocytoma Cells
67

Nakagoshi M; Takikawa S, Tsusue M
Relationship between Seasonal Color Dimorphism and Pteridines in the Scorpion Fly, Panorpa japonica, Thunberg
69

Koller M, Schramm G, Goldberg M
Effects of Environmental Conditions on Urinary Biopterin and Catecholamines in Rates
71

Cremer-Bartels G, Gerding H, Krause K, Yektapour-Tabrizi M
Reduced Pterins of the Retina in Response to Light Exposure
75

Ziegler I, Cotton R, Jennings I
Identification of Pterin Binding Sites on Class I HLA Molecules Associated with the Interleukin 2 Receptor
77

Rokos H, Wiegers P, Leonhard M, Ahmed JS
Biopterin and Neopterin Serum Levels in Trypanosoma-infected dogs
79

Rokos K, Rokos H, Pauli G
Mechanism of Interferon Induction and Pteridine Production in HIV-Infection
83

Schott K, Gütlich M, Maier J, Werner T, Ziegler I
Cytokines and Viral Gene Products as Regulators of Pterin Synthesis in Cells of the Immune System
85

Sawada Y, Shintaku H, Nakajima T, Iwamura C, Tsubakio Y, Fujioka M, Nishimura A, Isshiki G, Ohura T, Kawakatu M; Nakamura T
New Pteridine Assay System Using Automated Squential Trace Enrichment of Dialysates
87

Nishimura A, Fujioka M, Katoh T, Nakajima T ,Shintaku H, Isshiki G, Sawada Y
Biopterin and Neopterin in Various Milks and Infant Formulas
89

Fischer B, Strähle J, Viscontini M
Pterin Chemistry, Part 91. Synthesis and Crystal Structure of the First Molybdenum (IV)-q-dihydro-L-Biopterin Complex
91

Armarego WLF, Kosar-Hashemi B
Glyceryl Etherase (EC 1.14.16.5) from Rat Liver: A Convenient Assay for Structure-Activity
Relationship Studies
95

Fitzhugh AL, Akee RK
A New Scalable Route to Resolvi
ng the α-Monoesters of d1 5 Formyl 5,6,7,8-tetrahydropteroylmono-L-Glutamic Acid
99

Cheung HTA, Dong Z, Smal M, Tattersall MHN
Synthesis and Properties of N-(α-Aminoacyl) Derivatives of Methotrexate
101

Cheung HTA, Chau DD, Morrison JF, Birdsall B, Feeney J
13C-Labelled Folates as NMR Probes of the Binding of Folates to Bacterial Dihydrofolates Reductases
103

Ivery MTG, Gready JE
Isomer Distributions and Seperation of 6- and 7-Methyl-8-Alkyl Pterins

105

Jeong SS, Gready JE
NMR Studies of the Structures and Degradation of 8 (2`-Hydroxyethyl) Pterins
109

Koen MJ, Gready JE
Progress on the Unambiguous Synthesis of 8-Methyl-7,8-dihydropterin
113

Wong SD, Gready JE
Use of SCX HPLC in the Study of 8-Alkyl-Pterins and their Reduced Derivatives
115

Kavallaris M, Haber M, Norris MD, Matherly LH, Stewart BW
Characterization of Mechanisms Mediating Drug Resistance in Human Leukemic Cells Selected with High Concentration Methotrexate
119

Nixon PF, Waltham MC
Interactions of Methotrexate, Trimetrexate and Piritrexim with Human and L. casei Dihydrofolate Reductases-Steady State Inhibition Constans and Dissociation Rates

123

Vitols KS, Haenseler E, Montejano Y, Baer T, Huennekens FM
Activation of Methotrexate Prodrugs by Enzyme/Monoclonal Antibody Conjugates
125

Appleman JR, Spencer HT, Villafranca JE
New Insights into the Roles of Critical Residues in the Active Site of Thymidylate Synthase: Results from Site-Directed Mutagenesis Interpreted in Light of a “High-Resolution” Kinetic Mechanism for Wild-Type Enzyme

127

Fan J, Vitols K, Huennekens FM
Affinity Purification of Folate Transport Proteins Using Biotin Derivatives of Methotrexate and Folate
131

Sant ME, Lyons SD, Phillips L, Szabados E, Christopherson RI
Inhibition of Amido Phosphoribosyltransferase by Antifolates in Mouse L1210 Leukaemia Cells

133

Blakley RL, Appleman JR, Tsay JT, Beard WA, FeisheimJH, Ayling JE, Jablonsky MJ
The Function of the Active Site Glutamate in Human Dihydrofolate Reductase

135

Cummins PL, Gready JE
Prediction of Relative Binding Constants of Cofactors and Designed Ligands to Dihydrofolate Reductase by Computer Simulation
137

Kohashi M, Akao K, Watanabe T
Biochemical Effects of Folate Radiated with the Mild Energy of Far-Infrared Waves
141

Noronha JM, Kesavan V, Viswanathan G
Antiatherogenic Effect of Folic Acid in Alcoholism
143

Laurence KM
Preconceptional Supplementation with Folic Acid to Prevent Recurrences and Occurences with Neural Tube Defects
145

Newman EM, Letvak LA,George MJ, Doroshow JH
Pharmacokinetics of High Dose Continuous Infusion (6S)-Folinic Acid in Humans
147

Hyland K, Surtees R
Measurement of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using HPLC with Coulometric Electrochemical Detection

149

Bottiglieri T, Hyland K, Laundy M, Godfrey P, Carney MWP, Toone BK, Reynolds EH
Folate, Homocysteine and Monoamine Metabolism in Depression
151

Aaron JJ, Gaye D, Parkanyi C, Boniface C Bieze TWN, Atik SS, Raghu Veer KS, Szentpaly L, Ghosh R
Solvent Effects upon the Electronic Absorption and Fluorescences Spectra of Pteridines and Riboflavin and their Ground and First Excited Singlet-State Dipole Moments
153

Nakanishi A, Goto M, Kato S, Sueoka T
6-Acetonylisoxanthopterin: A Potent Inhibitor of Sepiapterin Reductase
165

Zangerle R, Fuchs D, Reibnegger G, Artner-Dworzak E, Fritsch P, Wachter H
Neopterin and the Acute Phase Response in Human Immunodeficiency Virus Type1 (HIV 1) Infection 
167

Escriche B, Silva FJ
An in Vitro System for Studying Pteridine Biosynthesis in Drosphila melangaster
171

Ruiz-Vazquez P, Bel Y, Garcia AM, Cabello ML, Dalmau J, Alos T, Catala JL, Ferre J
Measurement of Neopterin and Biopterin in Urine from Phenylketonuria Heterozygotes and Normal Controls
177

Strohmaier W, Bahrami S, Davies J, Redl H, Schlag G
Neopterin and Tumor Necrosis Factor a: Two Markers of Monocyte/Macrophage Activation in a Septic Baboon Model
181

Cox J, Armstrong A, Blair JA
The Influence of 2,4-Diamino-6-Hydroxypyrimidine and Food Restriction on Tetrahydrobiopterin Metabolism, Neurotransmitters and Behaviour in the Rat
185


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1993, volume 4

Blau N, Thöny B, Heizmann CW, Dhondt JL 
Tetrahydrobiopterin Deficiency: From Phenotype to Genotype
1

Pfleiderer W
Pteridines XCVIII: Synthesis and Properties of 1-Methylpterins
11 

Sugimoto T, Pfleiderer W
Pteridines IC: Chemical Synthesis and Structural Proof of Photinuspterin


Reibnegger G, Denny BJ, Wachter H
Ab Initio Quantum Chemical Calculations on the Stability of Different Tautomers of 6- and 7-Phenacetyl Pterin
23 

Katoh S, Sueoka T, Kurihara T
Theoretical Stereostructure of the Neutral Form of Natural Tetrahydrobiopterin
27 

Jeong S, Wormell P, Gready JE 
Investigation of Spectra and Ionization Constants of 8-Alkyl Pterins by Fluorimetry
32 

Samsonov MY, Reibnegger G, Nassonov EL, Nassonova VA, Wachter H, Fuchs D
Elevated Serum Neopterin Levels in Acute Rheumatic Fever
39 

Yoon KH, Cha KW, Park SI, Yim JJ
Isolation and Characterization of Sepiapterin Reductase from Drosophila melanogaster
43 
Shavit FM
Folinic Acid Enhanced Cytotoxicity of Fluoropyrimidines in Human Breast Cancer Cells
51 

Balinska M, Natorff R, Paszewski A
Regulation of Folate Metabolizing Enzymes in Fungus Aspergillus niduland
56 

Sehgal
Ethylenediamine Spacer between Methotrexate and Poly(D-lysine): A Probe for Exploring pH-Sensitivity of a Lysosomotropic Conjugate 
60 

Hariu T, Okamoto M, Arai M, Goto M,
6-(D-ribo-tetrahydroxybutyl)-pterin from Rhodopseudomonas spaeroides
63

Lapanant S, Pholcharoen T, Thuvasethakul P, Leohirun L
Neopterin and Its Clinical Significance in Autoimmune Diseases
67 

Hettich RL, Jacobson KB
Characterization of Underivatized Pterins by Laser Desorption Fourier Transform Mass Spectrometry
72 

Ichiyama A, Oguro K, Hasegawa H
Intracellular Tryptophan Hydroxylase Activity Assessed by Metabolic Assay: An Interpretation of in vitro Activation of the Enzyme
76 

Kornhuber HH, Westarp MP Wachter H, Rasmussen H, Clausen J, Hoff-Jörgensen R, Bartmann P, Fuchs D, Westarp ME
Neopterin, β2-Microglobulin and Carbohydrate Antigen CA-19-9 in Sporadic Adult Amyotrophic lateral Sclerosis
81 

Hikita H, Masada M, Sueoka T, Katoh S
6-Lactoyl Tetrahydropterin, as well as 6-Hydroxyacetonyl Tetrahydropterin (Katoh Pterin), is also an Intermediate between PPH4 and BH4 in the Reaction of Sepiapterin Reductase 
90 

Abstracts: 12th International Winter-Workshop an Biochemical and Clinical Aspects of Pteridines
February 13th – 20th, 1993, St. Christoph, Arlberg, Austria

93

Viscontini M, Heizmann CW, Bosshard R
Synthesis of 6β-N(5)-Methyl-5,6,7,8-tetrahydro-L-biopterin
115 

Pfleiderer W, Al-Masoudi NAL
Nucleosides LIII Syntheses and Reactions of 6,7-Dipyridyllumazine and 2´-Deoxylumazine N-1 Nucleosides
119 

Fuchs D, Wachter H, Weiss G, Reibnegger G, Jurika G, Rudzite V
Influence of Kynurenine, Neopterin, Noradrenaline and Pyridoxal-5-Phosphate on Cholesterol and Phospholipid Content and Phospholipid biosynthesis in vitro
126 

Nájera C, Millán JM
Mutagenesis at Five Pteridine Pathway Loci in Drosophila melanogaster: Genetic and Biochemical Characterization
131 

Bngtsson A, UnanderM, Haeger M
Neopterin, PMN Elastase, and Complement Components as Monitoring Parameters in Women with the Syndrome of Homolysis, Elevated Liver Enzymes and Low Platelet Count
138 

Dapunt O, Wachter H, Herold M, Fuchs D, Schröcksnadel H
Activated Macrophages in Pre-eclampsia
144 

Fuchs D, Wachter H, Fritsch P, Kofler P, Benedikter S, Sepp N
Cyclosporin A Treatment in Psoriasis: Monitoring by Neopterin Concentrations in Serum and Urine
149 

Rokos H, Hunsicker A, Weissenhofer W, Kullich W
Immune Stimulation of Interferon-Gamma- and Biopterin Synthesis with Endotoxin in Animal-Experimental Peritonitis
153

Grimshaw CE, Matthews DA, Yuong NH, Varughese KI, Whiteley JM
Dihydropteridine Reductase
159 

Melichar B
Asociation between Urinary Zinc and Neopterin Excretion: A Manifestation of the Acute Phase Response in the Kidney?
174 

Pfleiderer W, Aritomo K, Eisele R
Synthesis and Properties of Lumazine-6- and –7-carboxylic Acids
178 

Fitzhugh AL
Sterioelectronic Effects in the O2-mediated Autoxidation of Reduced Folate Derivatives 
187 – 191

Fuchs D, Wachter H, Mailath G, Hönlinger M, Bernhart TH, Andersson CH
Immune Activation after Apicoectomy: Comparison between Patients with and without Prophylactic Antibiotic Therapy
192 

Fuchs D, Wachter H, Artner-Dworzak E, Zangerle R, Melichar B
Are Disturbances of Zinc Metabolism in Human Immunodeficiency Virus Type 1 (HIV-1) Infection Caused by Immune Activation?
195 

Fuchs D, Wachter H, Fridrich L, Moncayo R, Mayersbach P, Zaknun J
Neopterin Levels in Thyroid Pseudocysts
200 

Viscontini M, Hesse M, Bosshard R, Schäfer A, Fischer B
New Results on the Chemistry of Metal-Tetrahydro-Pterin Complexes
206 

Yim JJ, Lee YK, Park SI, Cha KW
Capillary Electrophoretic Separation of Pteridine Compounds
210

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1994, volume 5


Armarego WLF, Taguchi H, Kosar-Hashemi B
Glyceryl-ether Monooxygenase (EC 1.14.16.5) Part V: Some Aspects of the Stoichiometry


Bacher; Eisenreich W
Biosynthesis of Methanopterin in Methanobacterium thermoautotrophicum 


Shintaku H
Early Diagnosis of 6-Pyruvoyl-tetrahydropterin Synthase Deficiency


Abstracts: 7th International Conference on Pteridines and Related Biogenic Amines
February 13th – 17th, 1994, Rusutsu Resort, Hokkaido, Japan

28 

Reibnegger G, Wachter H, Schönitzer D, Werner ER, Fuchs D, Schennach H, Augustin R, Mayersbach P
Applicability of an Enzyme-linked Immunosorbant Assay for Neopterin Detection for Screening of Blood Donations
49 

Graczyk J
Effect of 5-Fluorouracil Administered at Low Doses on Cytotoxic Properties of Methotrexate in the in vivo Model of Mice L1210 Leukemia - According to the Schedule of Treatment
55 

Zilkens KW, Zimmermann S, Schweitzer K, Peters M
Neopterin Determinations in Tuberculous Bone Infections
61 

Abstracts: 13th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 19th – 26th, 1994, St. Christoph, Arlberg, Austria

65

Armarego WLF, Yang N, Paal B, Taguchi H, Kurisu T
Glyceryl-ether Monooxygenase [EC 1.14.16.5] Part VII Effects of Alkyl Phosphocholines and Acyl L-α-lyso-Phosphatidylcholines Detergents on Enzyme Activity
95 

Fuchs D, Wachter H, Unsinn K, Zaknun J, Zaknun D
Interferon Gamma-induced Formation of Neopterin and Degradation of Tryptophan in Cerebrospinal Fluid of Children with Meningitis but Not with Febrile Convulsions
102 

Graczyk J
Effect of Folate-deficient Diet and 5-Fluorouracil Treatment in the in vivo Model of Mice L1210 Leukemia
107 

Ohbayashi A, Iino T, Kimura H, Nojiri N, Mazda T
Plasma Neopterin in Hepatitis C Virus Antibody–positive and –negative Donors with Elevated Alanine Aminotrasferase Activity
111 

Blair JA, Williams A, Wachter H, Fuchs D, Pall H, Armstrong RA, Winsper SJ
Serum Neopterin Levels and Metal Binding to Transferrin in Parkinson´s Disease Patients
114 

Holownia E, Mysliwiec M, Markiewicz W, Kozlowska H, Boron-Kaczmarska A
Neopterin Levels in Blood Serum and Bile in Acute and Chronic Liver Disease
117

Pfleiderer W, Wagner T, Koul A
Synthesis and Characterization of Dimeric Lumazines
121 

Pawlczak K, Rzeszotarska B, Kempny M
Synthesis of N-(4-propargylaminobenzoyl)-L-glutamates
129 

Voboril Z, Malirova E, Mergancova J, Vavrova J, Jandik P, Melichar B
Serum Neopterin and Angiotensin-converting Enzyme in Cancer Patients
133 

Fuchs D, Wachter H, Dierich MP, Soelder B, Neugebauer J, Zaknun D
Immune Activation and HIV-1 Viraemia in an Asymptomatic Paediatric Patient
136 

Reibnegger G, Wachter H, Wick G, Xu Q
Relationship among Serum hsp65 Antibodies, Neopterin, Autoantibodies and Atherosclerosis
139 

Kornhuber HH, Wachter H, Westarp MP, Fuchs D, Westarp ME
Neopterin, β2-Microglobulin, Tryptophan and Kynurenine in Sporadic Amyotrophic Lateral Sclerosis
142

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1995, volume 6

Pfleierer W, Qizheng Y, Yamamoto H, Soranaka K, Torigow K, Hanaya T
Selective N(3)-and O4-Alkylation of L-Biopterin : A convenient Synthesis of 3-and O4-Methyl-L-biopterin and the Versatile N2-(N,N-dimethylaminomethylene)-N(3)-p-nitrophenethyl-Protected L-Biopterin


Schlag G, Wachter H, Redl H, Werner ER, Strohmaier W
Plasma Nitrate and Pteridine Levels in Experimental Bacteremia in Baboons


Fuchs D, Waschter H, Frede S, Fandrey J, Jelkmann W, Schobersberger W
Neopterin-induced Suppression of Erythropoietin Production In Vitro
12 

Abstracts: 14th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 11th – 18th, 1995, St. Christoph, Arlberg, Austria

17

Pawelczak K, Rzeszotarska B, Kempny M
An Improved Synthesis of t-Butyl N-(4-propargylaminobenzoyl)-γ-oligo-(L-glutamate)s
41 

Armarengo WLF, Paal B, Taguchi H
Glyceryl-Ether Monooxygenase [EC 1.14.16.5] Part VIII, Probing the Nature of the Active Site
45 

Yim J, Park D, Kim H, Kim N, Park YS
Expression and Characterization of Recombinant Drosophila 6-Pyruvoyl-tetrahydropterin Synthase
58 

Noronha JM, Viswanathan G, Katki KA
Role of Folate in the Modulation of Lipids, Lipoproteins and Eicosanoids in Hypertension and Diabetes
63 

Fuchs D, Wachter H, Baier-Bitterlich G, Jurika D, Rudzite V
Effect of Sepiapterin, 7,8-Dihydrobiopterin, 5,6,7,8-Tetrahydrobiopterin and Xanthopterin on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in vitro
69 

Peters KM, Klosterhalfen B, Schälicke S, Koberg K
Neopterin n Septic Arthritis
74 

Duru S, Kansu E, Isimer A, Koc Y, Akpek G, Sahin G, Altindag Z
Urinary Neopterin Levels as an Indicator of Disease Activation in Behcet´s Disease
79

Pfleiderer W, Gottlieb M, Melguizo M
Synthesis of New Pteridine Nucleosides and Nucleotides
85 

Viscontini M, Hegetschweiler K, Schäfer A, Fischer B
Iron and Terahydropterin Complex with 1.2.3-Triamino-2,4,6,-trihydroxy-cyclohexane as Ligand
87 

Suckling CJ, Rice MJ, Gibson CL, Paulini K, Dunn C, Lang A
Pteridines and Purins as Probes and Inhibitors of Folate Biosyntheses
90 

Yim J, Kim SJ, Kang D
Purification and Characteristics of Enzymes in the Biosynthesis of Tetrahydrolimipterin (1-O-(L-erythro-5,6,7,8-tetrahydrobiopterin-2´-yl)-β-N-acetylglucosamine)
93 

Krause K, Gerding H, Cremer-Bartels G
Tetrahydromonapterin as Cofactor of Dopamine Synthesis in Retina
97 

Wood JM, Schallreuter-Wood KU
Control of Melanogenesis in the Human Epidermis by the Redox-Status of Tetrahydrobiopterins 
101 

Nagatsu T, Matalon R, Blau N, Ichinose H
Genomic Organization of Mouse and Human GTP Cyclohydrolase I Genes and Mutations Found in the Human Gene
104 

Bacher A, Ziegler I, Werner Th, Rödl W, Katzenmeier G, Witter K, Gütlich M
Functional Studies on the Promoter Region of the Human GTP Cyclohydrolase I Gene
108 

Ninnemann H, Werner Th, Maier J
Homology Cloning of GTP-cyclohydrolase I from Fungi and Plants by Reverse-transcription PCR Using a General Set of Degenerate Primers
112 

Gütlich M, Ziegler I
Control of GTP cyclohydrolase I Activity during Aggregation of Dictyostelium discoideum
116 

Yim J, Kim N
Cloning of Drosophila purple Gene and Expression in E. coli: Purple Gene Encodes PTP Synthase
119 

Ghisla S, Heizmann CW, Curtius HC, Macheroux P, Thöny B, Köster S
Characterization of Human Pterin-4a-carbinolamine Dehydratase/Dimerization Cofactor of Hepatocyte Nuclear Factor-1α, and of the Cys81-mutant Involved in Hyperphenylalaninaemia
123 

Minama N, Hasegawa H, Ueha T, Kurihara K, Matsumoto R, Nakanishi N
Effect of H-7, a Protein Kinase Inhibitor, on Cyclic AMP-Dipendent Inhibition of Monoamine Transport in PC12 Cells
126 

Pfeilschifter J, Blau N, Redweik U, Kunz D, Plüss C
Co-ordinate Expression of GTP Cyclohydrolase I and Inducible Nitric Oxide Synthase in Rat Masangial Cells
129 

Levine RA, Kuhn DM, Louie MC, Imerman BA, Anastasiadis PZ
Mitogenic Effects of Tetrahydrobiopterin: Involvement of Catecholamine and Nitric Oxide Synthesis
132 

Silva FJ, Ruiz – Vazquez P, Alcaniz S
Evidence of the Phenylalanine Hydroxylase Involvement in Biosynthesis of Pteridines and Hydroxylation of Tryptophan in Drosophila melanogaster
135 

Nakanishi N, Watabe S, Oguro K, Kohima M, Hasegawa H
Rapid Turnover of Tryptophan Hydoxylase: Demonstration of Proteolytic Process in Cell-free System
138 

Blau N, Heizmann CW, Brandt NJ, Scheibenreiter S, Leimbacher W, Thöny B, Oppliger T
Mutation Analysis in Patients with 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency
141 

Ponzone A, Lanza C, Ferraris S, Blau N, Schuler A, Spada M
Deprenyl in 6-Pyruvoyl Tetrahydropterin Synthase Deficiency
144

Hagberg L
The Clinical Use of Cerebrospinal Fluid Neopterin Concentrations in Central Nervous System Infections
147

Pfleiderer W, Flatmark T, Haavik J, Almas B, Groehn V, Heizmann G
Synthesis of 6-Azidomethy1-5,6,7,8-tetrahydropterin: Photodegradation Products and Cofactor Properties on Aromatic Amino Acid Monooxygenases
153

Kiguchi K, Murat S, Sugimoto T
Reaction of Pteridine and its 8-Oxide with Grignard Reagents, Regioselctive 7_alkylation of Pteridine
160

Koike M, Uemura S, Minatogawa Y, Kamisako H, Hatanaka Y, Suzuki H, Ohishi K, Iizuka T
The High Concentration of Biopterin in Breast Milk and Its Absorption During the Neonatal Period
168 

Koshimura K, Miwa S
6R-L-erythro-5,6,7,8-Tetrahydrobiopterin and Dopamine Release
173

Kojima S
Neopterin as an Endogenous Antioxidant
181

Blair JA, Winsper SJ, Cattell RJ, Armstrong RA
The Levels of Neopterin, Biopterin and The Biopterin/Neopterin Ratio in Urine from Control Subjects and Patients with Alzheimer’s Disease and Down’s Syndrome
185

Sawada M
Neopterin in Immunological Reactions in Cancer and in the Brain - Possible Involvement of Macrophages and Microglia
190

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1996, volume 7


Mauritz W, Poigenfürst J, Stohmaier W
Neopterin Blood Levels: A Basis for Deciding to Use Antibiotics in Intensive Care Unit (ICU) Patients


Tsutomu O, Kosuke J, Nobuyuki S, Tadashi S
The Regulation of Neopterin Production by Cytokines


Kesavan V, Viswanathan G, Pote MS
Impaired Folic Acid Metabolism Leading to Increased Urinary Folate Loss in Steptozotocin-induced Diabetic Rats
10 

Armarego WLF, Hanssen K, Yang N
The Sepuence of Mouse Dihydropteridine Reductase cDNA, and Comparison with Human and Rat Sequences
14 

Fuchs D, Wachter H, Baier-Bitterlich G, Jurika E, Rudzite V
Effect of 7,8-Dihydroneopterin, Biopterin and Isoxanthopterin on Cholesterol and Phospholipid Content and Phospholipid Biosynthesis in Vitro
24 

Fuchs D, Wachter H, Baier-Bitterlich G, Möller AA, Diez-Ruiz A
Neopterin Production, Degradation of Tryptophan and Neurologic Impairment in Human Immunodeficiency Virus Infection
29 

Nakanishi N
Regulation of Intra- and Extracellular Biopterin Levels of PC12 Cells in Culture by Cyclic AMP: Stimulation of Biosynthesis and Inhibition of Transport
35

Abstracts: 15th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 24th – March 2nd, 1996, St. Christoph, Arlberg, Austria

39

Shane B, Jukes T, Carpenter K, Blair JA
Memorials of Prof. Dr. E. L. Robert Stokstad
69 

Koike M, Uemura S, Oishi K, Kamisako H, Sasaki M, Iizuka T
The Augmented Productions of Neopterin and Cytokines from Macrophages/monocytes in vitro
72 

Graczyk J
Chronopharmacokinetics of Methotrexate in Mice: Modulation by Administration of 5-Fluorouracil in Combination Chemotherapy
77 

Thompson E, Feldmann M, Bell J, Giovannoni G
Increased Urinary Neopterin Excretion in Vaccinated Adults
82 

Selected Papers: 9th International Conference on Pteridines and Related Biogenic Amines
19th-24th May, 1996, Port Douglas, Australia (edited by: Blau N, Christodulou J)

88

Armarego W
Glyceryl-ether Monooxygenase (EC1.14.16.5) A Mixed Function Oxidase Requiring Oxygen and a Tetrahydropterin Cofactor
90

Kluge C, Leimbacher W, Heizmann C, Blau N, Thöny B
Isolation of 6-Pyruvoyl-tetrahydropterin Synthase cDNAs from Human Brain
91

Kojima M, Iida Y, Yamamoto K, Oguro K, Nakanishi N, Watabe S, Hasegawa H
Rapid Turnover of Tryptophan H
ydroxylase: The Turnover Rate is Unaffected after Elevation of the Enzyme Amount Induced by Treatment of Cells with Calcium Ionophores and Protease Inhibitors
94

Köster S, Stier G, Fichner G, Curtius HC, Suck D, Ghisla S
Three Histidines in Pterin-4a-carbinolamine Dehydratase are the Important Residues for Substra
te Binding and Catalysis
98

Lehbauer J, Pfleiderer W
Syntheses of 8-(β-D-2-Deoxyribofuranosyl)-isoxanthopterin
101

11th International Symposium on Chemistry and Biology of Pteridines and Folates
Organized by Pfleiderer W, Rokos K and Rokos H

L de Sanctis, Alliaudi C, Spada M, Cerone R, Biasucci G, Blau N, Ponzone A, Dianzani I
Mutations and Phenotypes in Dihydropteridine Reductase Deficiency in Italy
103

Spada M, Blau N, Meli C, Ferrero GB, L de Sanctis, Ferraris S, Ponzone A
Different Strategies in the Treatment of Dihydropteridine Reductase Deficiency
107

Yamamoti H, Hanaya T, Harada K, Kawamoto H, Pfleiderer W
An Efficient Synthesis of Limipterin (2`-O-(2-Acetamido-2-deoxy-β-D-glucopyranosyl)-L-biopterin) via N2-(N,N-Dimenthylamino)-methylene-3-(2-(4-nitrophenyl)ethyl)-L-biopterin
110


Pfleiderer W, Abou-Hadeed K
Pteridines CVIII
Reactions of 6,7-Dichloro-1,3-dimethyllumazine with Sulfur-Nucleophiles
113 

Armarego WLF, Yang n, Zhang H
In vitro Mutagenesis of Human Dihydropteridine Reductase at the Active Site and at Altered Sites Found in the Reductases of Deficient Children
123 

Cremer-Bartels G
Degeneration of Rat Retina is Paralleled by an Imbalance of the Redox Mechanism of Pteridines
137 

Viswanathan G, Parameswaran Nair CP, Kulkarni MV
Varying Folate Pattern in Different Strains of Mice Fed Coconut Oil and Sesame Seed Oil Diet
143 

Hirose H, Yasumura M, Taguchi O, Kito T, Morimoto T, Sawada S
5,6,7,8-Tetrahydroneopterin (NH4) Acts like an Endogenous Superoxide Dismutase
148 

Hasegawa m, Mukawa J, Yamashiro K, Ishida A
Tetrahydrobiopterin-dependent Production of L-DOPA in Genetically Modified Primary Fibroblasts: Basic Research of Gene Therapy for Parkinson’s Disease
151 

Hasegawa H, Nakanishi N, Nagano M, Yamamoto K
A Comparison of Sepiapterin and Tetrahydrobiopterin Uptake by RBL2H3Cells
154 

Kojima S, Mori K, Mori H, Ishii H, Arai T
Effects of Neopterin on Focal Cerebral Ischemia in Rats
157 

Tsusue M, Lino T, Mazda T
Urinary and Serum Pteridines in Liver Diseases
160

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1997, volume 8


Murakami K, Sugimoto T, Murata S
Preparation and Synthetic Application of Highly Reactive 6-Trifluoromethane-sulfonyloxylumazine; a Novel Method for 6-Substituted Lumazines


Ikekita M, Iizuka H, Oyobe S, Kugenuma H, Kojima S
Suppressive Effect of Tetrahydrobiopterin on L-β-(3,4-Dihydroxyphenyl)-alanine-induced Cytotoxicity in PC-12 Cells
10 

Fuchs D, Wachter H, Mitterschiffthaler G, Czarnecki M, Fuith LC
Abdominal Hysterectomy Induces Immune Activation
17 

Reibnegger G, Vrecko K, Öttl K, Möller R, Daczi J, Horejsi R
Inhibitory Effects of Pteridines on the Cytochrome P-450 Enzyme System
21

Abstracts: 16th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 16th-February 22nd, 1997, St. Christoph, Arlberg, Austria 

27

Abstracts: 11th International Symposium on Chemistry and Biology of Pteridines and Folates
June 15th – 20th, 1997 Berchtesgaden, Germany

57

Bertino JR, Queener SF, Forsch RA, Rosowsky A
Synthesis of 2,4-Diaminopteridines with Bulky Lipophilic Groups at the 6-Position as Inhibitors of Pneumocystis carinii, Toxoplasma gondii, and Mammalian Dihydrofolate Reductase
173 

Pfleiderer W, Murata S, Seo C, Sugimoto T
Regioselective Arylation of 1,3-Dimthyllumazine and Its 5-Oxide by Deazonium Salts
188 

Schobersberger W, Hoffmann G, Jelkmann W, Hobisch-Hagen P, Wiedermann F, Herold M, Mair J, Deetjen C
Time Course of Neopterin and Cytokines After an Extreme Bicycle Race at Moderate Altitude
195 

Fuchs D, Wachter H, Weiss G, Herpfer I, Jirgensons J, Jurika E, Rudzite V
The Influence of Kynurenine and Its metabolites on Lipid Metabolism
201 

Kuzuya H, Fujita K, Sakamoto H
Influence of an Aromatic Amino Acid Decarboxylase Inhibitor on GTP Cyclohydrolase I Activity in the Rat Brain
206 

Reibnegger G, Vrecko K, Mlekusch W, Lamprecht M
Influence of Three Different Diet Modes Combined with Exercise Loads on Urinary and Plasma Neopterin Concentrations: A Longitudinal Study
211 

Graczyk J
Experimental Study Evaluating the Effect of Combined Methotrexate and Fluorouracil Therapy on Anemia in Mice With L1210 Lymphoid Leukemia
216

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1998, volume 9


Bengtsson A, Bengtson JP, Ronholm E, Tomasdottir H
Release of Neopterin, PMN Elastase and Terminal Complement Complexes by Orthotopie Liver Transplantation with and without the Use of Veno-Venous Bypass


Kasai K, Gross SS, Nakanish N, Hattori Y
Tetrahydrobiopterin Synthesis in Rat Cardiac Myocytes; an Event Required for Cytokine-Induced NO Generation


Wakasugi K, Kojima S, Hoshi H, Araki S, Hiramoto M, Aizawa S
In Vivo Stimulatory Effects of Neopterin on Hematopoiesis
13 

Takikawa S, Iino T, Dohke K, Nakagoshi M, Kanekatsu M, Sawada H
Purification and Characterization of Sepiapterin Deaminase from the Silkworm, Bombyx Mori
18 

Okuyama A, Takahara S, Miki T
Correlations of Serum and Urine Levels af Neopterin, IL-8, IL-6, IL-6R, Basic Fetoprotein and Hepatocytes Growth Factor with Acute Rejection in Kidney Transplantation
22 

Mori K, Kojima S, Suzuki T, Ishii H, Mori H, Arai T
Auto-oxidation of 5,6,7,8-Tetrahydroneopterin
26 

Tanaka N, Nitta Y, Hizuta A, Iwagaki H
Altered Tryptophan and Neopterin Metabolism in Cancer Patients
29 

Kojima S
Effects of Tetrahydrobioptrein (BH4) on S-Nitroso-N-acetyl-D,L-penicillamine (SNAP)-induced HL-60 Cell Death
33 

Fujita K, Sakamoto H, Kuzuya H
Influences of Catecholamine Contents on Tetrahydrobiopterin Metabolism
39 

Flatmark T, Pfleiderer W, Vageli O, Martinez A
Proton NMR Studies on the Conformation of the Pterin Cofactor Bound at the Active Site of Recombinant Human Tyrosine Hydroxylase
44

Armarego WLF
A Twenty Year Association with Pteridines – Chemistry, Biochemistry and Molecular Biology
55 

Yim J, Kim S, Kang D
Biosynthetic Enzymes of Tetrahydrolimipterin from Green Sulfur Bacterium Chlorobium Limicola
69 

Mlekusch W, Oettl K, Horejsi R, Reibnegger G
Electronic Charge Density and Electrostatic Potential of Pterin, 7,8-Dihydropterin and 5,6,7,8-Tetrahydropterin – an Ab initio Quantum Chemical Study
85 

Fuchs D, Wachter H, Wirleitner B, Wede I, Baier-Bitterlich G, Widner B
Neopterin: Indicator of Oxidative Stress and Part of the Cytotoxic Armature of Activated Macrophages in Humans
91 

Fuchs D, Reibnegger G, Widner B, Baier-Bitterlich G, Jurika E, Rudzite V
Pteridines and Lipid Metabolism
103 

Müller TF, Lange H, Reibnegger G, Gemsa D, Grebe SO, Sprenger H, Neumann MC
Neopterin, Serum Amyloid A, and Cytokine Montioring After Renal Transplantation
113 

Publication List of Prof. Wolfgang Pfleiderer (in Pteridine field)
123

Abstracts: 17th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 14th-21st, 1998, St. Christoph, Arlberg, Austria 

145

Pfleiderer W, Abou-Hadeed K
Synthesis and Properties of 1,3-Dimethyllumazine-6,7-diamines
175 

Cossins EA, Wrishko RE
Inhibition of Mycelial Growth by Methotrexate in Neuropora crassa Wild Type and Mutants Deficient in Folylpolyglutamate Synthase
181 

Klosterhalfen B, Peters KM
Neopterin in Bone Banking
192 

Yanchev I, Chowdhury I, Katzarova E, Dikov A, Ralchevsky V, Toshkova R, Zvetkova E
Protective Effect of Ranopterin Neopterin on Experimentally induced Graffi Tumours in Hamsters
196 

Fuchs D, Weiss G, Widner B, Jirgensons J, Jurika E, Rudzite V
Difference and Similarity of Serotonin and Pteridines to Act on Lipid Metabolism
201 

Fuchs D, Widner B, Rudzite V, Martinsons A
Neopterin an Kynurenine in Mesangioproliferative Glomerulonephritis
207 

Osawa N, Mazda T, Fukuda A, Yoshimoto S
Serum Neopterin Assay to Interpret the Main Cause of Chronic Liver Damage Involved with Plural Etiological Factors
212 

Krezel I, Guzowski G, Graczyk J
Wxperimental Studies of the Effect of Cyclic Mitoguazone Analogues on Antineoplastic Activity of Methotrexate
217 

Wilkin T, Rokos H, Barley J, Braven J, Galloway T
Serum Biopterin as a Marker of Immune Activation in the Spontaneously Diabetic BB Rat
222

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1999, volume 10


Hasegawa H, Nakanishi N, Oguro K, Nagano M, Yamamoto K, Nakazawa N
6R-L-erythro-Tetrahydrobiopterin Triggers Serotonin Release with 5HT-loaded RBL2H3 Cells, a Rat Mast Cell Line


Togari A, Mogi M, Ichinose H, Nagatsu T
Neopterin and Cytokines in Hereditary Dystonia and Parkinsons’s Disease


Yamamoto T, Kiuchi Y, Momose K, Shimizu S, Ishii M
Characterization of the Protective Effect of Tetrahydrobiopterin Against S-Nitroso-N-Acetyl-D,L-Penicillamine Induced Endothelial Cell Injury
14 

Tanaka N, Takakura N, Isozaki H, Kobashi K, Hizuta A, Iwagaki H
Clinical Value of Neopterin in Infectious Complications
20 

Narita T, Hirano S, Sato T, Wawada M, Ozaki N, Kusunoki K
Serum Levels of Dihydroneopterin and Soluble Cytokine Receptors in Major Depression
24 

Hashimoto K, Fujino O, Fujita T, Kuwabara K, Fukunaga Y, Kawakami Y
Cererospinal Fluid Levels of Neopterin in Child Patients with Neurological Diseases in Correlation with IFN-γ or TNG-α
27 

Fukuda K, Suzuki T, Endo N, Ishii H, Arai T, Mori H
Pterin-6-aldehyde, Xanthine Oxidase Inhibitor and Superoxide Scavenger, Directly React with Peroxynitrite
32 

Murata R, Asada M, Shintaku H, Sawada Y, Tomiwa K, Kawawaki H, Kurimasa H, Togawa M, Shiomi M
Neopterin Concentrations of Serum and Cerebrospinal Fluid in Febrile Convulsion, Aseptic Meningitis and Influenza Encephalopathy
35 

Rosowsky A, Bader H, Forsch R
Synthesis of L-2-(N-Pteroylamino)-3-(N-phosphonoacetyl)aminopropanoic Acid as an Analogue Folylpolyglutamate Synthetase
39

Abstracts: 18th International Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
March 6th – 13th, 1999, St. Christoph, Arlberg, Austria 

47

Pfleiderer W, Traub H
Pteridines CX
Synthesis and Properties of 6-Substituted 2,4-Diaminopterines and Pterins
79 

Werner ER, Pauschenwein J, Reibnegger G
Electronic Structure of Tetrahydropteridine Derivatives
91 

Moser R, Groehn V
Synthesis of Optically Pure Diasterioisomers of Reduced Folates
95 

Fuchs D, Baier-Bitterlich G, Spöttl N, Mayr Ch, Wirleitner B, Murr C, Widner B
The Importance of Neopterin as a Laboratory Diagnostic Marker of Immune Activation
101 

Werner-Felmayer G, Werner ER, Peterbauer A
Neopterin and Nitrite in Supernatants from Interferon-γ-treated Monocytoid Cell Lines: A Tool to Identify Bacterial Pyrogens
112 

Fuchs D, Tilz GP, Wirleitner B, Samsonov MY, Nassonov EL
Neopterin in Autoimmune Rheumatic Diseases
119 

Schobersberger W, Fuchs D, Margreiter J, Innerhofer P, Wiedermann FJ
Procalcitonin and Neopterin in Infectious Diseases
125 

Fuchs D, Widner B, Jurika D, Rudzite V
Similarity Between the Action of Pteridines and Tryptophan metabolites on Lipid Metabolism
133 

Graczyk J, Wiewiorowski M
Methotrexate in Treatment of Rheumatoid Arthritis
141 

Prof. Helmut Wachter (List of Publications)
149

Chen L, Nargang F, Cossins E
Isolation and Sequencing of a Plant cDNA Encoding a Bifunctional Methylenetetrahydrofolate Dehydrogenase: Methenyltetrahydrofolate Cyclohydrolase Protein

171

Zvetkova E
Ranopterins-Amphibia Skin Pteridines Displaying Hematopoietic, Immunomodulatory, and Macrophageal Proliferative Biological Activities

178

Vrecko K, Walzl M, Tafeit E, Reibnegger G
Relationship Among Serum and Urine Neopterin, Fibrinogen, and Other Serum Analytes in Artherosclerotic Patients and the Long-term Effect of H.E.L.P. Therapy
190


Kondera-Anasz Z, Mertas A
Level of Serum Neopterin and Interleukin-6 in Patients with Thyroid Diseases
197

Iizuka H, Sagara H, Kojima S
Modulation of LPS-induced Cell Death by 5,6,7,8-Tetrahydrobiopterin
202

Fukuda A, Tsuda Y, Yoshimoto S, Mazda T
Serum Neopterin Monotoring in Hepatitis Be Antigen Positive Chronic Type B Hepatitis with Recurrent Acute Exacerbation

207

Ishii M, Shimizu S, Nagai T, Kiuchi Y, Yamamoto T
Insulin Stimulates Tertrahydrobiopterin Synthesis in Mouse Brain Microvascular Endothelial Cells
213

Widner B, Fuith LC, Czarnecki M, Fuchs D
Correlation of Neopterin Concentrations in Amniotic Fluid and Urine of Pregnant Women at Delivery

217

Sattler W, Leblhuber F, Walli J, Widner B, Fuchs D
Cerebrospinal Fluid levels of α-tocopherol and Neopterin in Patients with Dementia
220


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2000, volume 11

Abstracts: 19th international Winter-Workshop on Biochemical and Clinical Aspects of Pteridines
February 12th -19th, 2000, St.Christoph, Arlberg, Austria 

1

Thorolfsson M, Fojan P, Petersen S-B, Martinez A
The Effect of Tetrahydrobiopterin on the Thermostability of Human Phenylalanine Hydroxylase as Studied by Circular Dichroism Spectroscopy
29

Martinez A, Dao K-K, Mc Kinney J, Teigen K, Froystein NA
The Conformation of 5,6,7,8-Tetrahydrobiopterin and 7,8-Dihydrobiopterin in Solution: a NMR Study
32

Flatmark T, Erlandsen H, Bjorgo E, Sostad T, Doskeland A, Stevens RC
Regulatory Properties of Tetrahydrobiopterin Cofactor Bound at the Active Site of Phenylalanine Hydroxylase
34

Hosp M, Quigley M, Mwinga AM, Godfrey-Faussett P, Porter JDH, McAdam KPWJ, Fuchs D
Neopterin and Other Indicators of HIV Progression in Zambian Adults
37

Gaonzales-Calvin J, Tilz GP, Gallego-Rojo F, Torres-Almendros M, Widner B, Diez-Ruiz A, Richo-Irles J, Fuchs D 
Neopterin, Soluble Receptors for Interleukin-2 and Tumor Necrosis Factor in Viral Cirrhosis and Alcoholic Cirrhosis
43

Leblhuber F, Walli J, Tilz GP, Demel U, Widner B, Fuchs D
Peripheral Immune Activation in Alzheimer’s Disease
48-53

Nassonov EL, Samsonov MY, Tilz GP, Chichasova NV, Widner B, Demel U, Nikiphorova EL, Fuchs D
Neopterin, Soluble Adhesion Molecules and Soluble Cytokine Receptors Correlate with Disease Activity in Rheumatoid Arthritis
54

Oettl K, Greilberger J, Reibnegger G
Dihydroneopterin and the Generation of Superoxide from Irons Ions
60

Kesavan V, Pote MS, Anand R, Viswanathan G
Variations in Folate Metabolism in Whole Body a-Irradiated Mice 
64

Leeming RJL
Memorials of Prof. Dr. John A.Blair
73

Schennach H, Meyersbach P, Schönitzer D, Fuchs D
Additional Neopterin Screening to Improve Safety of Blood Donations
76

Fujimoto K, Inaba A, Tomomura A, Katoh S
Determination by Site-directed Mutagenesis of Sites in Sepiapterin Reductase Phosphorylated by Ca2+/Calmodulin-dpendent Protein Kinase II
81

Shinataku H, Asada M, Sawada Y, Yamano T
Tetrahydrobiopterin Responsive Hyperphenylalaninemia Without Biopterin Deficiency
83

Wirleitner B, Kowald E, Widner B, Ortner U, Baier-Bitterlich G, Sepp N, Fuchs D
Soluble fas Ligand and Neopterin in Patients with Systemic and Cutaneous Discoid Lupus erythematosus 
85

Oettl K, Greilberger J, Reibnegger G
Dihydroneopterin as a Scavenger of Nitrogen-centered Radicals
90

Laganovska G, Martinsons A, Pitrans B, Widner B, Fuchs D
Neopterin and Kynurenine Concentrations in Aqueous Humour of the Anterior Chamber of the Eye and in Serum of Cataract Patients with Pseudoexfoliation
94

Lorente C, Thomas AH, Villata LS, Hozbor D, Lagares A, Capparelli AL
Photoinduced Cleavage of Plasmid DNA in the Presence of Pterin
100

Rudzite V, Jurika E, Jäger M, Fuchs D
Impairment of Lipid Metabolism Due to Deficiency of Pyridoxal-5-phosphate and/or Activated Immune System: its Interpretation
107

Hasegawa H, Yamamoto K, Matsuhashi Y, Miyazawa T, Nakanishi N, Ogura K
Ability of RBL2H3 Cells to Lower Environmental Tetrahydrobiopterin Concentration

121

Furujo M, Ichiba Y, Sintaku H, Asada M
A Case of Dihydropteridine Reductase Deficiency
126

Shiota K, Ishii M, Yamamoto T, Shimizu S, Kiuchi Y
Stimulation of Tetrahydrobiopterin Synthesis by 17ß-Estradiol in Brain Microvascular Endothelial Cells

129

Yoshida N, Ikemoto S, Keisuke, Narita K, Sugimura K, Wada S, Yasumoto R, Nakatani T
Serum Neopterin Levels in Renal Cell Carcinoma
133

Ishii M, Shimizu S, Shiotam K, Kiuchi Y, Yamamoto T
Troglitazone Stimulates the Insulin-induced Tetrahydrobiopterin Synthesis in Vascular Endothelial Cells
137

Kawakami Y, Kuwabara K, Fujita T, Fujino O, Fukunaga Y
Neopterin and Cytokines in Non-pleocytotic Cerebrospinal Fluid in Child Patients

142


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2001, volume 12


Abstracts: 20th International Winter-Workshop on Clinical, Chemical, and Biochemical Aspects of Pteridines, February 10th - 17th , 2001; St.Christoph, Arlberg, Austria
1

Abstracts: 12th International Symposium Chemistry and Biology of Pteridines and Folate
s
June 17th - 22nd, 2001, Bethesda, MD, USA 
29

Walter R, Schaffner A, Schoedon G
Tetrahydrobiopterin in the Vascular System
93

Choi YK, Hwang YK, Kang YH, Park YS
Chemical Structure of 1-O-(L-Erythro-biopterin-2’-yl)-a-glucose isolated from a Cyanobacterium Synechococcus sp. PCC 7942
121

Ledochowski M, Murr C, Lass-Flörl C, Fuchs D 
Helicobacter pylori Infection and Neopterin
126

Rudzite V, Silava A, Kalnins U, Erglis A, Jäger M, Trushinskis K, Fuchs D
Association between Increased Serum Neopterin and Homocysteine Concentrations as well as Pyridoxal-5-phophate Deficiency in Patients with Coronary Heart Disease
130

Zvetkova E, Fuchs D, Katzarova E, Bakalska M, Svetoslavova M, Nikolov B
Neopterin Acting as a Bone Marrow Stem Factor on Early Common 
Haematopoietic (Myeloid) and Stromal (Dendritic, CD34+) Cell Progenitors in vitro
135

Rieder J, Amann A, Schloesser M, Czechowski M, Seibel M, Marth C, Hoffmann G.
Supptessive Effects of Neopterin on Inducible Nitric Oxide Synthase Gene Expression in Ovarian Carcinoma Cells in vitro.
140

Demel U, Földes-Papp Z, Fuchs D, Tilz GP
Characterization of Pteridines: a New Approach by Fluorescence Correlation Spectroscopy and Analysis of Assay Sensitivity
147

Ledjeff E, Artner-Dworzak, Witasek A, Fuchs D, Hausen A
Neopterin Concentrations in Colon Dialysate
155

Masakazu I, Shimizu S, Nagai T, Kazuhiro S, Kiuchi Y, Yamamoto T
Negative Regulation of Insulin-induced Tetrahydrobiopterin Synthesis by Protein Kinase C in Vascular Endothelial Cells
161

Vrecko K, Pfragner R, Siegl V, Schauenstein K, Reibnegger G
Effect of Interferon-g and LPS on Tetrahydrobiopterin in Rat PC 12 and Human KNA Cells 
167

Kesavan V, Singh N, Pote MS, Viswanathan G
Synthesis and Regulation of Folate Coenzymes During early Germination in Vigna radiata
172

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2002, volume 13


Stahl-Hennig C, Fendrich C, Lüke W, Widner B, Hunsmann G, Fuchs D
Urinary Neopterin Indicates early Infection and Disease Progression: Model Studies with Simian and Human Immunodeficiency Viruses in Macaques
1

Sperner-Unterweger B, Miller C, Holzner B, Laich A, Widner B, Fleischhacker W, Fuchs D
Immunologic Alterations in Schizophrenia: Neopterin, L-Kynurenine, Tryptophan and T-Cell Subsets in the Acute Stage of Illness
9

Gunga HC, Machotta A, Schobersberger W, Mittermayr M, Kirsch K, Koralewski E, Röcke L
Neopterin, IgG, IgA, IgM, and Plasma Volume Changes During Long-distance Running
15

Shiota K, Shimizu S, Ishii M, Yamamoto S, Iwasaki M, Yamamoto T, Kiuchi Y
Hydrogen Peroxide Stimulates the LPS-induced Tetrahydrobiopterin Synthesis in Mouse Brain Microvascular Endothelial Cells
21

Hattori Y, Nakanishi N, Suzuki M, Yoshida M, Kasai K 
3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Enhance Cytokine-mediated Induction of Nitric Oxide Synthesis in Vascular Smooth Muscle Cells
26-31

Shimizu S
Protective Effect of Tetrahydrobiopterin Against Reactive Oxygen Species- and Nitric Oxide-induced Vascular Endothelial Cell Injury 
32

Abstracts: 21st International Winter-Workshop Clinical, Chemical, and Biochemical Aspects of Pteridines
February 23rd-March 2nd, 2002; St.Christoph, Arlberg, Austria 

39

Abou-Hadeed K, Pfleiderer W
Synthesis and Properties of Condensed Lumazine-Ringsysteme
65

Földes-Papp Z
Theory of Measuring the Selfsame Single Fluorescent Molecule in Solution Suited for Studying Individual Molecular Interactions by SPSM-FCS
73

Kojima S, Kurozumi R, Tuchiya M
A New Functional Role of 5,6,7,8-Tetrahydrobiopterin (BH4) as an inhibitor of g-glutamylcysteine synthetase (g-GCS) mRNA expression
83

Masakazu I, Shunichi S, Kazuhiro S, Shinichiro Y, Kjuchi Y, Yamamoto T
Stimulation of Tetrahydrobiopterin Synthesis by Cyclosporin A during Lipopolysaccharide Treatment in Vascular Endothelial Cells 
89

Vrecko K, Reibnegger G
Influence of 7,8 Dihydroneopterin and Hyperoxia on Neurite Growth and Tyrosine Hydroxylase Activity of PC 12 Cells 
94

Rudzite V, Jurika E, Kalnins U, Erglis A, Trusinskis K, Jegere S, Frick B, Fuchs D
Comparing the Sensitivity of Pyridoxal-5-phosphate, Homocysteine and Neopterin in Coronary Heart Disease
100

Baydar T, Papp A, Nagymajtenyi L, Schulz H, Sahin G
Folate supplementation in rats: Does it Cause Behavioural and Electrophysiological Changes?
107

Horejsi R, Möller R, Tafeit E, Reibnegger G
Neopterin, Dihydroneopterin, Tetrahydroneopterin: Different Structures - Increasing Capacity Cleaving the Porphyrin in Heme Proteins
115

Laich A, Leblhuber F, Widner B, Frick B, Jellinger K, Fuchs D
Moderate Hyperhomocysteinemia in Patients with Huntington’s Disease
121

Mueller NJ, Walter RB, Linscheid P, Schaffner A, Schoedon G
Differential Inhibition of Constitutive and Inducible Nitric Oxide Synthase in Vascular Endothelial Cells by Analogues of Tetrahydrobiopterin
126

Schennach H, Murr C, Gächter E, Mayersbach P, Schönitzer D, Fuchs D
Association Between Neopterin Production and other Parameters in a Population of Blood Donors
133

Weiss G, Diez-Ruiz A, Murr C, Theurl I, Fuchs D
Tryptophan Metabolites as Scavengers of Reactive Oxygen and Chlorine Species
140

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2003, volume 14


Iwanaga N, Yamamasu S, Tachibana D, Nishio J, Nakai Y, Shintaku H, Imanaka M, Yamano T, Ishiko O
Plasma Levels of Neopterin and Biopterin in the Umbilical Vessels and the Maternal Vein
1

Kawakami Y, Sakamoto M, Shimada KI, Noguchi E, Kuwabara K, Fukui-Kobayashi F, Shirota K, Ogawa KI, Fujita T, Fujino O, Kojima S, Fukunaga Y
Correlation between Neopterin, Biopterin and Nitrite/Nitrate in Cerebrospinal Fluid in Child Patients with Neurological Diseases
5

Shimizu S, Miyasaka Y, Yamamoto S, Ishii M, Kiuchi Y
Stimulation of Tetrahydrobiopterin Synthesis by Basic Fibroblast Growth Factor in Vascular Edothelial Cells
9

Shinozaki K, Kashiwagi A, Masada M, Okamura T
Molecular Mechanisms of Endothelial Dysfunction in the Insulin-Resistant State:
the Roles of Abnormal Pteridine Metabolism
13

Chan SY, Cossins EA
The Intracelluar Distribution of Folate Derivatives in Pea Leaves
17

Houcher B, Candito M, Gibelin P, Caramella A, De Courcy GP, Naimi D, Lefebvre JC, Van Obberghen E
Assessment of Folate Status: Measurement of Homocysteine versus Vitamin B12 and Folate
27

Winkler C, Wirleitner B, Werner ER, Fuchs D
Urinary Neopterin Concentrations in Healthy Individuals with Household Contact 
35

Abstracts: 22nd International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines
February 22nd - March 1st, 2003; St.Christoph, Arlberg, Austria, 

41

Chan SY, Cossins EA
The Intracellular Distribution of Folate Derivates in Pea Leaves 
67

Bodur A, Baydar T, Ozmeric N, Engin AB, Uraz A, Eren K, Sahin G
Neopterin Profile to Evaluate the Effectiveness of Treatment in Aggressive Periodontitis
77

Frick B, Rudzite V, Schröcksnadel K, Kalnins U, Erglis A, Trusinskis K, Fuchs D
Homocysteine, B Vitamins and Immune Activation in Coronary Heart Disease
82

Frick B, Neurauter G, Diez-Ruiz A, Schroecksnadel K, Wirleitner B, Leblhuber F, Fuchs D
Neopterin and Oxidation Products in the Blood of Patients with Various Forms of Dementia
88

Zieba R, Czarnecka E, W1growska-Danilewicz M, Dzielska-Olczak M, Graczyk J
Effects of Carnosine on the Toxicity of Doxorubicin in Rabbits and Mice
94

Winkler C, Frick B, Schroecksnadel K, Wirleitner B, Fuchs D
Follow-up of Urinary Neopterin Concentrations in Two Healthy Children until Adolescence
102

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2004, volume 15


Neurauter G, Wirleitner B, Schroecksnadel K, Schennach H, Fuchs D.
Wine and Grape Juice Modulate Interferon-g-Induced Neopterin Production and 
Tryptophan Degradation In Human PBMC. 


Muranishi S, Soyka R And Pfleiderer W.
Aldol-Type and Claisen Condensation Reactions Of 1,3,6- And 1,3,7- 
Trimethyllumazines
10

Kondera – Anasz Z, Sikora J, Mertas A Micinski P, Bednarz B.
Concentrations of Neopterin and Interleukin-10 In Peritoneal Fluid and in 
Serum of Women with Endometriosis
20

Pagel H, Hoffmann G, Fuchs D, Schobersberger W. 
On the Mechanisms of the Neopterin-Induced Suppression of Renal Erythropopietin 
Production 
28

Gülmen B, Turgan N, Kayikcioglu M, Özmen D, Ersöz B, Kültürsay H.
Comparative Assessment of The Diagnostic Value of Neopterin and Acute Phase 
Proteins in Angiographically Assessed Stable Coronary Artery Disease
33

Abstracts: 23rd International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines
February 28th - March 6th, 2004; St.Christoph, Arlberg, Austria 

45

Schroecksnadel K, Murr C, Winkler C, Wirleitner B, Fuith LC, Fuchs D. 
Neopterin to Monitor Pahthologies Involving Interferon-g Production. 
75

Leitner S, Golderer G, Winkler C, Fuchs D, Werner-Felmayer G, Werner ER. 
Interferon-g-Induced Growth Inhibition of Neuroblsastoma Cells is Independent 
Of Nitric Oxide Synthase And Indoleamine (2,3)-Dioxygenase. 
91

Oettl K, Greilberger J, Reibnegger G.
Modulation of Free Radical Formation By Pterin Derivates
97

Hagberg L, Andersson LM, Abdulle S, Gisslen M.
Clinical Application of Cerebrospinal Fluid Neopterin Concentration in HIV 
Infection
102

Hoffman G, Schobersberger W.
Neopterin: a Mediator of the Cellular Immune System
107

Grebe SO, Kuhlmann U, Müller TF.
Elevated Post-Transplant Levels of Neopterin are Associated with Poorer Long-
Term Graft Outcome
113

Weiss G.
Linkage of Pteridine Metabolism to Iron Homeostasis
120

Döring T, Boruah RC, Pfleiderer W
Pteridines, CXV. Synthesis of 7-Acyl-2,4-Disubstituted Pteridines by Radical Nucleophilic Substitution and Displacement Reactions
129

Schobersberger W, Hoffmann G, Fries D, Gunga HC, Greie S, Fuchs D, Klingler A, Humpeler E
AMAS (Austrian Moderate Altitude Study) 2000: Effects of Hiking Holidays at Moderate Altitude on Immune System Markers on Persons with Metabolic Syndrome
149

Batra V, Kesavan V, Mishra KP
Modulation of Folate Dependent DNA Methyltransferase 1 (Dnmt1) Activity in Whole Body g-Irradiated Mice
155

Tsuda Y, Fukuda A, Kobayashi H, Itou D, Yoshimoto S, Iwata K, Hanafusa T
Serum Neopterin as a Marker for Screening of Hepatocellular Carcinoma
161

Murr C, Hainz U, Asch E, Berger P, Jenewein B, Saurwein-Teissl M, Grubeck-Loebenstein B, Fuchs D
Increased Neopterin Concentration in Older Age Coincides with Decline of CD28+CD45RA+ T-Cells
170

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2005, Volume 16



Nakanishi N, Kurihara K, Tomomura1 A, Tonosaki K, Hattori Y, Oguro K, Hasegawa H. 
Increase in Tetrahydrobiopterin Release from Pc12 Cells Under Hypotonic Culture Conditions is Inhibited By HgCl2
1

Sawabe K, Suetake Y, Wakasugi KO, Hasegawa H.
Intestinal Uptake of 6(R)-L-Erythro-Tetrahydrobiopterin is Distinctive from The Liver-Type MTX-Sensitive Accumulation Process
6

Sawada H, Shimura N, Takikawa SI, Iino T.
Possibility of The Nonenzymatic Conversion of 6-(1’-Oxo-2’-Hydroxypropyl)-Tetrahydropterin to Sepiapterin
11

Rudzite V, Jurika E, Schroecksnadel K, Kalnins U, Erglis A, Trusinskis K, Fuchs D.
Usefulness of Neopterin, C-Reactive Protein, Homocysteine, Pyridoxal-5-Phosphate, and Phospholipid Determination in Coronary Artery Disease
15

Candito M, Houcher B, Roux F, Potier De Courcy G, Caramella A, Berthier F, Aberkane A, Van Obberghen E
Influence of Meal on Plasma Folate And Vitamin B12, by Three Methods – and on Vitamin B6, Homocysteine and Red Blood Cell Folate
22

Teigen K, Jensen VR, A Martínez A.
The Reaction Mechanism of Phenylalanine Hydroxylase - a Question of Coordination
27

Licastro F, Chiappelli M, Porcellini E, Ruscica M, Corsi MM
Neopterin Levels and Immune Activation in the Blood of Children With Down’s Syndrome
35

Abstracts: 13th International Symposium on Chemistry and Biology of Pteridines and Folates
June 20th - 24th, 2005; Egmond Aan Zee, The Netherlands

41 

Abstracts: 24th International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines
February 27th - March 6th, 2005; St.Christoph, Arlberg, Austria 

125

Batra V, Kesavan V, Mishra KP. 
Modulation of DNA Methyltransferase1 Profile by Gamma Irradiation Followed by Methyl Donor Starvation 
159

Rieder J, Marth C, Schobersberger W, Hoffmann G. 
Neopterin as a Stimulator of Vascular Endothelial Growth Factor and Erythropoietin Gene Expression in an Ovarian Carcinoma Cell Line
166

Cermanová M, Melichar B, Solichová D, Bláha M, Bláha V, Blažek M, Mašín V, Cerman J, Zadák Z
Urinary Neopterin and Microalbuminuria in Patients Treated by Low-Density Lipoprotein Apheresis 
174

Arendt R, Pfleiderer W. 
Pteridines, CXVI. [1] Synthesis and Reactivity of 6-Substituted 1,3-Dimethyl-7-Hydroxylumazines and 7-Substituted 1,3-Dimethyl-(5H)-Lumazin-6-Ones
184

Rudzite V, Jurika E, Fuchs D, Kalnins U, Erglis A, Trusinskis K
Inflammation, Homocysteine, Pyridoxal-5-Phosphate and Lipids in Patients with Coronary Artery Disease Before and Six Months after Coronary Angioplasty Followed by Stent Implantation
190

Neurauter G, Wirleitner B, Schennach H, Ueberall F, Fuchs D
A Herbal Multicomponent Mixture Effective in Suppressing Biochemical Pathways in Mitogen-Stimulated Human Peripheral Blood Mononuclear Cells
195

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2006, volume 17

Murata S, Chen M
Difference of DNA Compaction Performed by Two kinds of Oncopterin-Mimic Pteridine - Polyamine Conjugates
1

Shimizu S, Ishii M, Wajima T, Hagiwara T, Negoro T
Beneficial Role of Tetrahydrobiopterin on Various Cardiovascular Diseases and Regulation of its Levels under Pathological Conditions
5

Shinozaki K, Kashiwagi A, Masada M, Okamura T
Tetrahydrobiopterin and Endothelial Dysfunction in Cardiovascular Diseases
11

Ahn C, Kim M, Lee S, Kim J, Hwang D, Park K, Yim J
Molecular Analysis of mps Operon Involved in Monapterin Synthesis in Escherichia coli
16

Bohuslav Melichar B, Dagmar Solichová D, Iveta Svobodová I, Lubor Urbánek L, Melicharová K
Urinary Neopterin in Patients with upper Gastrointestinal, Biliary and Pancreatic Carcinomas
20

Huber L, Winkler C, Schroecksnadel K, Geser W, Schubert C, Fuchs D
Serial Analysis of Tryptophan Degradation and Neopterin Formation in an otherwise Healthy Individual before and during an Infectious Episode
25

Abstracts: 25th International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines
March 5 - 12th, 2006; St.Christoph, Arlberg, Austria 
33

Hattori Y, Nakanishi N
Statin Increases GTP Cyclohydrolase I mRNA and 5,6,7,8-Tetrahydrobiopterin in Vascular Endothelial Cells
65

Ishii M, Shimizu S, Watabe T, Kiuchi Y
Tetrahydrobiopterin Regulates L-tyrosine-induced Elevation of Cytosolic Calcium Concentration in Insulin-secreting Cells
69 

Hori M, Kojima S
Effect of 5,6,7,8-Tetrahydrobiopterin (BH4) on g-Ray-induced Micronucleus Frequency in RAW264.7 Cells
74

Petroselli G, Bartsch JM, Thomas AH
Photoinduced Generation of H2O2 and O2·- by 6-formylpterin in Aqueous Solutions
82

Bjelakovic G, Pavlovic D, Jevtovic T, Stojanovic I, Sokolovic D, Bjelakovic GB, Nikolic J, Bašic J
Vitamin B12 and Folic Acid Effects on Polyamine Metabolism in Rat Liver
90

Rudzite V, Jurika E, Erglis A, Trusinskis K, Jegere S, Fuchs D

Intravascular Ultrasound Data and Results of Serum Biochemical Indices at the Time of Stenting and after Six Months in Patients with Coronary Artery Disease
95

Leeming RJ, Hall SK

Folate Metabolism and the Role of Dihydropteridine Reductase (DHPR)
101

Renneberg R, Chan CP, Nie YM, Leung MF, Bergmann A, Ip M, Rainer T, Schennach H
Neopterin Screening to Improve Safety of Blood Transfusion
103 

Parrak V, Secnik P, Skrakova M
Neopterin Screening of Blood Donations
105

Melichar B, Solichova D, Melicharova K, Cermanova M, Urminska H, Ryska A
Systemic Immune Activation, Anemia and Thrombocytosis in Breast Cancer Patients Treated by Doxorubicin and Paclitaxel
107

Rieder J, Marth C, Hoffmann G
Effect of Neopterin Derivatives on Mitochondrial Dehydrogenase Activity in Ovarian Carcinoma Cell Lines in Vitro
115

Schobersberger W, Sumann G, Mittermayr M, Griesmacher A, Falkensammer G, Greie S, Schobersberger B, Hoffmann G, Fuchs D, Koller A

Muscle Trauma and Immune Activation after a Downhill Marathon (Tyrolean Speed Marathon)
121

Tilz GP, Wiltgen M, Demel U, Faschinger C, Scherbichler W
New Insights into Ophthalmology: Introduction of SELDI-TOF in Combination with Molecular Modelling for the Analysis of Aqueous Humour.
Principle and First Results.
129

Schroecksnadel K, Gruber B, Frick B, Jenny M, Ledochowski M, Leblhuber F, Fuchs D
Long-term Supplementation with B Vitamins does not Change Plasma Neopterin Concentrations in Demented Patients
135

Melichar B, Urbanek L, Krcmová L, Kalabova H, Svobodova I, Dragounova E, Vesely P, Hyspler R, Solichova D
Urinary Neopterin in Patients with Ovarian Cancer
145


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2007, volume 18

Melichar B, Kalabova H, Urbanek L, Malirova E, Solichova D
Serial Urinary Neopterin Measurements Reflect the Disease Course in Patients with Epithelial Ovarian Carcinoma Treated with Paclitaxel/Platinum Chemotherapy
1

Houcher Z, Boudiaf K, Benboubetra M, Houcher B
Effects of Methanolic Extract and Commercial Oil of Nigella sativa L. on Blood Glucose and Antioxidant Capacity in Alloxan-Induced Diabetic Rats
8

Plata-Nazar K, Luczak G, Borkowska A, Delinska-Galinska A, Kozielska E, Marek K, Korzon M
Reference Standard of Serum Neopterin Concentration in Healthy Children
19

Melichar B, Touskova M, Hornychova H, Vokurkova D, Solichova D, Vesely D, Mergancova J, Urminska H, Ryska A
Systemic Immune Activation and Peripheral Blood Lymphocytes during Primary Chemotherapy with the Combination of Doxorubicin and Paclitaxel in Patients with Breast Carcinoma

25

Abstracts: 26th International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines
March 4th - 11th, 2007; St.Christoph, Arlberg, Austria 
35 

Schobersberger W, Gufler V,  Griesmacher A,  Bartenbach C, Canazei M, Staggl S, Hoffmann G
Effect of Two Different Lighting Environments on Urinary Neopterin and Sulphatoxymelatonin in an Experimental Night Shift Model
69

Wiltgen M, Tilz GP
A Basic M
olecular Analysis of the Diabetic Antigen GAD by Homology Modelling. Principles of the Method and Understanding of Antigenicity and Binding Sites
79

Kalábová H, Dvořák J, Hyšpler R, Tichá A, Krčmová L, Urbánek L, Solichová D, Melichar B
Urinary Neopterin in Patients Treated with Gefitinib
95

Harada T, Tsuboi I, Yuda M, Wakasugi K, Aizawa S
In vitro Effect of Neopterin on Splenic Mast Cell Development in Senescence Accelerated Mice (SAM)
101

A Modified Microbiological Method for Determination of Folate Levels in Erythrocyte and Plasma
Sipahi H, Baydar T, Ozalp M, Sahin G.
106

Kunihiro S, Hattori Y, Jojima T, Tomizawa A, Okayusu T, Kase H, Kawagoe Y, Banba N, Monden T, Nakanishi N, Kasai K
Tetrahydrobiopterin Slows the Progression of Atherosclerosis
115

Houcher B, Candito M, Gieblin P
Plasma total Homocysteine, Folate, and Vitamin B12 Status and Hospitalizations for Cardiovascular Disease
122

Melicharova K, Kusalová M, Smahelova A, Hyšpler R, Solichová D, Melichar B
Urinary Neopterin in Patients with Diabetes Mellitus and Foot Ulcers
128

Yuksel O, Sahin TT, Girgin G, Sipahi H, Dikmen K, Samur O, Barak A, Tekin E, Baydar T
Neopterin, Catalase and Superoxide Dismutase in Females with Benign and Malignant Breast Tumors
132

Schubert C, Neises M, Fritzsche K, Burbaum C, Geser W, Ocaña-Peinado FM, Fuchs D, Hass
R, Schmid-Ott G
Preliminary Evidence on the Direction of Effects between Day-to-Day Changes in Cellular Immune Activation, Fatigue and Mood in a Patient with prior Breast Cancer: A Time-Series Analysis Approach
139

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2008, volume 19

Program, 27th International Winter-Workshop on Clinical, Chemical, and Biochemical Aspects of Pteridines, St.Christoph, Arlberg, Austria, March 2nd - 9th, 2008
1

Vrecko K, Schwingenschuh P, Holl A, Saurugg R, Wenzel K, Katschnig P, Tafeit E, Ott E
Immunological Markers in Plasma and CSF distinguish Vascular Parkinsonism from Idiopathic Parkinson's Disease
7

Houcher B, Bourouba R, Djabi F, Houcher Z
The Prevalence of Neural Tube Defects in Sétif University Maternity Hospital, Algeria-3 Years Review (2004-2006)
11

Melichar B, Hyšpler R, Kalábová H, Urbánek L, Krčmová L, Solichová D
Gastrointestinal Permeability - a Parameter of Possible Prognostic Importance in Metastatic Colorectal Carcinoma
19

Plata-Nazar K, Łuczak G, Kamińska B, Bogotko-Szarszewska M, Renke J, Szumera M
Serum Neopterin Concentration in Children with Ulcerative Colitis
23

Abstracts: 27th International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines, St.Christoph, Arlberg, Austria, March 2nd - 9th, 2008
29

Melichar B, Ballóková A, Malířová E, Urbánek L, Krčmová L, Hyšpler R, Hornychová H, Ryška A, Solichová D
Circulating Vascular Endothelial Growth Factor, C-reactive Protein and Urinary Neopterin Concentrations During dose-dense Chemotherapy
65

Hanaya T, Torigoe K, Soranaka K, Fujita H, Yamamoto H, Pfleiderer W
An Efficient Synthesis of 2'-O-(b-D-Ribofuranosyl)biopterin
72

Neher A, Schobersberger W, Augustijns P, Fuchs D, Wolf-Magele A, Hoffmann G
Influence of Neopterin on Ciliary Beat Frequency of Human Nasal Epithelial Cells in vitro
79

Rehák S, Řehák S, Malířová E, Cermanová M, Šuba P, Cerman J, Plíšek S, Melichar B
Cerebrospinal Fluid Neopterin in Patients with Tumors and other Disorders
86

Ishii M, Shimizu S, Watabe T, Kiuchi Y
Insulin Secretion in Response to L-Arginine under Decreasing Tetrahydrobiopterin Content
93

Winkler C, Schroecksnadel K, Schennach H, Houcher B, Fuchs D
In vitro effects of Nigella sativa seeds extracts on stimulated peripheral blood mononuclear cells

101

Baydar T, Girgin G, Fuchs D, Inanici F, Sipahi H, Erol O, Sahin G
Pteridine pathway in patients with degenerative diseases during short time treatment with low dose of meloxicam, as a non-steroidal anti-inflammatory drug
107

Moser B, Schroecksnadel K, Hörtnagl H, Rieder J, Fuchs D, Gottardis M
Influence of extreme long endurance sports activity on neopterin excretion

114

Soniat M, Martin CB
Theoretical study on the Relative Energies of Neutral Pterin Tautomers*
120
*Received Publication Award 2008!*

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2009, volume 20

Program, 28th International Winter-Workshop on Clinical, Chemical, and Biochemical Aspects of Pteridines, St.Christoph, Arlberg, Austria, March 2nd - 9th, 2008
1

Abstracts: 27th International Winter-Workshop Clinical, Chemical & Biochemical Aspects of Pteridines, St.Christoph, Arlberg, Austria, March 2nd - 9th, 2008
7

Beneš P, Melichar B, Študentová H, Kapustová M, Malířová E, Schneiderka P, Šrámek V, Ćwiertka K
Serum Neopterin in patients with malignant melanoma
45

Cincibuch J, Melichar B, Študentová H, Kapustová M, Malířová E, Solichová D, Krčmová L, Kašparová M, Schneiderka P, Juráňová J, Šrámek V, Ćwiertka K
Serum neopterin, retinol and alpha-tocopherol in patients with the carcinoma of the esophagus
49

Ploder M, Spittler A, Schroecksnadel K, Neurauter G, Pelinka LE, Roth E, Fuchs D
Accelerated tryptophan degradation in trauma and sepsis patients is related to pro-inflammatory response and to the diminished in vitro response of monocytes
54
*Received Publication Award 2009!*

Schubert C, Lampe A, Geser W, Jenny M, Fuchs D
Temporal association between daily alcohol consumption, emotional states and urinary neopterin levels in a patient with systemic lupus erythematosus
62

Abstracts: 14th International Symposium on Pteridines and Folates
Jeju, Korea June 7~12, 2009
73

In vitro effect of neopterin on erythropoiesis in mice
Tsuboi I, Hokari T, Harada T, Yuda M, Aizawa S
115

Neopterin concentration in serum and chosen markers of inflammatory process in children with acute diarrhea caused by Rotavirus or Salmonella
Kozlowska-Murawska J, Obuchowicz A
119
*Received Publication Award 2009!*

Theoretical study on the relative energies of anionic pterin tautomers
Soniat M, Martin CB
124

Effect of neopterin on the hematopoietic system (a review)
Tsuboi I, Aizawa S
129

SPECIAL ISSUE
14th International Symposium on Pteridines and Folates
Jeju, Korea June 7~12, 2009

Hopkins Lecture
Kapatos G, Chandran N, Kfoury N
The Ups and Downs of GTP Cyclohydrolase I: A Neuroscience Point of View
S11

Pfleiderer W
Unexpected Reactions in Pteridine Chemistry
S18

Kuroda Y, Murata S
Synthetic Study of Methanopterin 1; Arylamination of 6-Acylpterin
S22

McInnes CR, Suckling CJ, Gibson CL, Raghavendar R, Morthala RR, Daff S, Gazur B
Blocked Dihydropteridines as Nitric Oxide Synthase Activators
S27

Hanaya T, Yamamoto H, Pfleiderer W
First Synthesis of a Representative, Natural Pterin Glycoside: 2?-O-(a-D-Glucopyranosyl)biopterin
S36

Siltberg-Liberles J, Flydal MI, Teigen K, Martinez A
Evolution of Regulation, Structure and Function in Phenylalanine Hydroxylase
S42

Werner ER, Hulo N, Watschinger K, Keller MA, Golderer G, Werner-Felmayer G
Alkylglycerol Monooxygenase Candidate Genes - Is There a Common Protein Motif for Tetrahydrobiopterin Interaction?
S51

Watschinger K, Keller MA, Golderer G, Hermetter A, Maglione M, Prast H, Werner-Felmayer G, Werner ER
Alkylglycerol Monooxygenase: Properties of an Orphan Enzyme - an Update
S55

Keller MA, Watschinger K, Golderer G,Maglione M, Werner-Felmayer G, Werner ER
Role of Fatty Aldehyde Dehydrogenase in Ether Lipid Degradation Pathways
S59

Blau N
Diagnosis of Inborn Errors of Tetrahydrobiopterin Metabolism
S64

Chang KC, Pae HO, Chung J, Joe Y, Hong SK, Chung HT
Roles of Heme Oxygenase-1 in the Antiproliferative and Antiapoptotic Effects of Nitric Oxide on Jurkat T Cells
S71

Maglione M, Oberhuber R, Cardini B, Hengster P, Hermann M, Obrist P, Werner-Felmayer G,
Werner ER, Margreiter R, Brandacher G
Ischemia Reperfusion Injury Following Solid Organ Transplantation: the Therapeutic Potential of Tetrahydrobiopterin
S78

Thöny B, Finnell RH
Murine Models for Inherited Disorders of Pterin, Monoamine Neurotransmitter and Folate Metabolism
S84

Sumi-Ichinose C, Ichinose H, Ikemoto K, Funami J, Nomura T, Kondo K
BH4 Metabolism in the Brains of BH4-synthesizing Enzyme KO Mice.
S99

Hopkins Lecture
Appling DR
Enzymology of Mammalian Mitochondrial One-Carbon Metabolism
S102

Jansen G, Mauritz R, Kathmann I, Boritzki TJ, Peters GJ
Membrane Transport Properties and Biological Activity of Stereo-isomers of Glycinamide Ribonucleotide Formyltransferase (GARFT) Inhibitors AG2032 and AG2034
S109

Peters GJ, Honeywell RJ, Leon LG, Van Groeningen CJ, Jansen G, Ylstra B, Meijer GA, Giovannetti E
Role of Pharmacodynamic, Pharmacogenetic and Pharmacogenomic Biomarkers of Cancer Chemotherapy with Antifolates
S115

Sigmond J, Todorova B, Smid K, Peters GJ
Cell Cycle Modulation Enhances the Cytotoxicity of Thymidylate Synthase Inhibitors
S128

Fraczyk T, Ruman T, Rut D, Dabrowska-Mas E, Ciesla J, Zielinski Z, Sieczka K, Debski J, Golos B; Winska P, Walajtys-Rode E, Shugar D, Rode W
Histidine Phosphorylation, or Tyrosine Nitration, Affect Thymidylate Synthase Properties
S137

Dabrowska M, Skoneczny M, Mosieniak G, Sikora E, Rode W
Expression of Cell Cycle Checkpoints Regulatory Genes During Methotrexate-Induced Senescence in Human Adenocarcinoma Cells
S143

De Brouwer V, Storozhenko S, Stove CP, Van Der Straeten D, Lambert WE
Determination of Folate Monoglutamates in Biofortified Rice with UPLC-MS/MS
S148

Gorman EB, Wallis D, Ballard JL, Goin-Kochel RP, Finnell RH
Folate Transport and Folate Responsive Developmental Disorders
S156

Dowiercial A, Jarmula A, Rypniewski W, Sokolowska M, Fraczyk T, Ciesla J, Rode W
Crystal Structures of Substrate- and Sulfate-Bound Mouse Thymidylate Synthase
S163

.…………………………………………………………………………………………………………………………...

2010, volume 21

Program, 29th International Winter-Workshop on Clinical, Chemical, and Biochemical
Aspects of Pteridines, St.Christoph, Arlberg, Austria, February 28th - March 2nd, 2010
1

Effect of Neopterin on Splenic Erythropoiesis in Mice
Tsuboi I, Harada T, Oshima H, Aizawa S
7

Serum Neopterin Concentration in Children with Viral Gastroenteritis
Plata-Nazar K, Luczak G, Gora-Gebka M, Liberek A, Kaminska B
11

Is There any Alteration in Erythrocyte Folate Status in Patients with Thyroid and Breast Cancers?
Baydar T, Sahin TT, Girgin G, Sipahi H, Yuksel O, Taneri F, Tekin E
17

Tilz GP, Wiltgen M, Hermetter A, Schmiedinger H, Demel U
Experiences with the SELDI-TOF Method for the Detection of the Diabetes Associated Antigen GAD 65 in the Peripheral Blood of Patients with Diabetes and Inflammation
22

Abstracts 29th International Winter-Workshop Clinical, Chemical, and Biochemical Aspects
of Pteridines, St.Christoph, Arlberg, Austria, February 28th - March 7th, 2010
29

Abstracts 24th Symposium of Japan Pteridine Meeting, RCMS Hall, Nagoya University, 
July
24th, 2010
67

Girgin G, Baydar T, Sahin TT, Palabiyik SS, Sipahi H, Yuksel O, Tekin E, Taneri F
Urinary Biopterin Levels and Blood Dihydropteridine Reductase Activities in Patients with Thyroid and Breast Disorders
72
*Received Publication Award 2010!*

Hanaya T, Hattori T, Takayama D, Yamamoto H
First Synthesis of a Natural Neopterin Glycoside: 3'-O-(?-D-Glucopyranosyluronic acid)neopterin
79

Leeming RJ, Hall SK
Dihydropteridine Reductase and Folate Metabolism Revisited
84

Melichar B, Kalábová H, Krcmová L, Kasparová M, Plísek J, Hyspler R, Studentová H, Zezulová M, Holecková P, Pecka M, Solichová D
Urinary Neopterin, Serum Retinol, a-tocopherol and Homocysteine in Breast Cancer Patients During Treatment with Bevacizumab and Chemotherapy
87

Hidayat BJ, Pedersen NA
Immune Modulation by Cross-Linked Bovine Colostrum in Vitro and in Vivo
94

Houcher Z, Houcher B, Touabti A, Begag S, Öztürk A, Egin Y, Akar N, Djabi F
Hyperhomocysteinemia and C677T Polymorphism of Methylenetetrahydrofolate Reductase Gene in Patients with Cardiovascular Disease
103

Engin AB, Karahalil B, Karakaya AE, Engin A
Exposure to Helicobacter pylori and Serum Kynurenine to Tryptophan Ratio in Patients with Gastric Cancer
110
*Received Publication Award 2010!*

.…………………………………………………………………………………………………………………………...

2011, volume 22

Program, 30th International Winter-Workshop on Clinical, Chemical, and Biochemical Aspects of Pteridines, St.Christoph, Arlberg, Austria, March 13th - March 20th, 2011
1

Expression of Neopterin and Chemokines in Rheumatoid Arthritis and Cardiovascular Disease
Fagerer N, Arnold M, Bernatzky G, Kullich W
7
*Received Publication Award 2011!*

Evaluation of Changes in Immune System of Operating Room Personnel by Measurement of Urinary Neopterin Concentrations
Baydar M, Capan Z, Girgin G, Baydar T, Sahin G
13

Effects of Inhalation Anesthetics on the Profile of Urinary Neopterin as an Immune Marker in Patients who Underwent Laparoscopic Cholecystectomy
Capan Z, Baydar T, Girgin G, Dolgun A, Dikmen B, Sahin G
18

Abstracts 30th International Winter-Workshop Clinical, Chemical, and Biochemical Aspects
of Pteridines, St.Christoph, Arlberg, Austria, March 13th - 20th, 2011
25

Erratum (Immune Modulation by cross-linked Bovine Colostrum in vitro and in vivo)
Ninfa R. Pedersen NR, Budi J. Hidayat BJ.
60

Urinary Neopterin in Patients with Metastatic Colon Cancer Treated with Patupilone
Melichar B, Kalábová H, Krcmová L, Kasparová M, Plísek J, Cerman J, Holecková P, Solichová D
61

Correlation of Peripheral Blood CD14+CD16+ Monocytes, Urinary Neopterin and the Risk Factors of Atherosclerosis in Patients with Breast Carcinoma
Králícková P, Kalábová H, Krcmová L, Kasparová M, Plísek J, Ungermann L, Vokurková D, Hyspler R, Pecka M, Srámek V, Studentová H, Zezulová M, Solichová D, Melichar B
66
*Received Publication Award 2011!*

Mechanistic Study of ROS-photogeneration by Pterin
Ji HF, Shen L
73

Clinical Usefulness of Determining the Concentration of Neopterin
Plata-Nazar K, Jankowska A
77

Neopterin may enhance TNF-alpha-mediated mononuclear cell death in the cerebrospinal
fluid of patients with bacterial meningitis
Kawakami Y, Tsukimoto M, Kuwabara K, Fujita T, Fujino O, Kojima S, Fukunaga Y
91

Hepatotoxicity and Langerhans Islets regenerative effects of polar and neutral lipids of
Nigella sativa L. in nicotinamide/streptozotocin-induced diabetic rats
Sobhi W, Khettal B, Belmouhoub M, Atmani D, Duez P, Benboubetra M
97

Folate measurement in mammalian tissues by fluorescence polarization
Martin H, Comeskey D
105

Electron transfer initiated reactions photoinduced by pterins
Lorente C, Petroselli G, Dántola ML, Oliveros E, Thomas AH
111

Chronic immune stimulation may cause moderate impairment
of Phenylalanine 4-hydroxylase
Scholl-Bürgi S, Schroecksnadel S, Jenny M, Karall D, Fuchs D
120